Evidence map›Paper›PMID 25852228›Full record

ArticleCanadian journal of veterinary research = Revue canadienne de recherche veterinaire2015

Staphylococcus spp., Streptococcus canis, and Arcanobacterium phocae of healthy Canadian farmed mink and mink with pododermatitis.

Gabhan Chalmers, John McLean, D Bruce Hunter, Marina Brash, Durda Slavic, David L Pearl, Patrick Boerlin

Open access · greenAbstract read
In one paragraph

Article in Canadian journal of veterinary research = Revue canadienne de recherche veterinaire, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Gabhan ChalmersDepartment of Pathobiology (Chalmers, McLean, Hunter, Boerlin), Animal Health Laboratory, Laboratory Services Division (Brash, Slavic), and Department of Population Medicine (Pearl), Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1.
John McLeanDepartment of Pathobiology (Chalmers, McLean, Hunter, Boerlin), Animal Health Laboratory, Laboratory Services Division (Brash, Slavic), and Department of Population Medicine (Pearl), Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1.
D Bruce HunterDepartment of Pathobiology (Chalmers, McLean, Hunter, Boerlin), Animal Health Laboratory, Laboratory Services Division (Brash, Slavic), and Department of Population Medicine (Pearl), Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1.
Marina BrashDepartment of Pathobiology (Chalmers, McLean, Hunter, Boerlin), Animal Health Laboratory, Laboratory Services Division (Brash, Slavic), and Department of Population Medicine (Pearl), Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1.
Durda SlavicDepartment of Pathobiology (Chalmers, McLean, Hunter, Boerlin), Animal Health Laboratory, Laboratory Services Division (Brash, Slavic), and Department of Population Medicine (Pearl), Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1.
David L PearlDepartment of Pathobiology (Chalmers, McLean, Hunter, Boerlin), Animal Health Laboratory, Laboratory Services Division (Brash, Slavic), and Department of Population Medicine (Pearl), Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1.
Patrick BoerlinDepartment of Pathobiology (Chalmers, McLean, Hunter, Boerlin), Animal Health Laboratory, Laboratory Services Division (Brash, Slavic), and Department of Population Medicine (Pearl), Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1.
University of Guelph · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pododermatitis is a disease of concern for mink breeders in Canada and worldwide, as it causes discomfort and lowers the breeding rates on farms affected by the disease. Unfortunately, the etiology and pathogenesis of pododermatitis are still unknown. In this study, we compared Staphylococcus spp. and Streptococcus canis isolates from healthy mink with isolates from animals with pododermatitis on 2 farms in Ontario. Almost all hemolytic Staphylococcus spp. isolated were shown to be Staphylococcus delphini Group A by 16S ribosomal ribonucleic acid (rRNA) sequence analysis and polymerase chain reaction (PCR). Pulsed-field gel electrophoresis (PFGE) did not reveal any S. delphini or S. canis clonal lineages specifically associated with pododermatitis, which suggests that these bacteria do not act as primary pathogens, but does not dismiss their potential roles as opportunistic pathogens. While S. delphini and S. canis were the most prevalent bacterial pathogens in mink pododermatitis, they were also present in samples from healthy mink. Arcanobacterium phocae is occasionally isolated from pododermatitis cases, but is difficult to recover with conventional culture methods due to its slow growth. A quantitative real-time PCR was developed for the detection of A. phocae and was tested on 138 samples of footpad tissues from 14 farms. The bacterium was detected only in pododermatitis-endemic farms in Canada and was at higher concentrations in tissues from infected footpads than in healthy tissues. This finding suggests that A. phocae is involved in the pathogenesis of pododermatitis.

Indexed as

Actinomycetales InfectionsAnimalsArcanobacteriumCanadaFoot DiseasesMinkReal-Time Polymerase Chain ReactionRNA, BacterialRNA, Ribosomal, 16SSkin Diseases, BacterialStaphylococcal Skin InfectionsStaphylococcusStreptococcal InfectionsStreptococcusRNA, BacterialRNA, Ribosomal, 16S

Identifiers

PMID25852228
PMCPMC4365704
OpenAlexW2417902026

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.