ArticleGenetics2015
Reconstructing Past Admixture Processes from Local Genomic Ancestry Using Wavelet Transformation.
Article in Genetics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed.
- The temporal and genomic scale of selection following hybridization.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- The temporal and genomic scale of selection following hybridization.bioRxiv : the preprint server for biology · 2023Article
- Article
- Adaptive introgression from indicine cattle into white cattle breeds from Central Italy.Scientific reports · 2020Article
- Dating admixture events is unsolved problem in multi-way admixed populations.Briefings in bioinformatics · 2020Article
- Sex-linked genetic diversity originates from persistent sociocultural processes at microgeographic scales.Royal Society open science · 2019Article
- Population Structure and Implications on the Genetic Architecture of HIV-1 Phenotypes Within Southern Africa.Frontiers in genetics · 2019Review
- Human ancestry indentification under resource constraints -- what can one chromosome tell us about human biogeographical ancestry?BMC medical genomics · 2018Article
- Article
- Complex Patterns of Admixture across the Indonesian Archipelago.Molecular biology and evolution · 2017Article
- Reconstructing Demography and Social Behavior During the Neolithic Expansion from Genomic Diversity Across Island Southeast Asia.Genetics · 2016Article
- Recent advances in the study of fine-scale population structure in humans.Current opinion in genetics & development · 2016Review
- Small Traditional Human Communities Sustain Genomic Diversity over Microgeographic Scales despite Linguistic Isolation.Molecular biology and evolution · 2016Article
- Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Admixture between long-separated populations is a defining feature of the genomes of many species. The mosaic block structure of admixed genomes can provide information about past contact events, including the time and extent of admixture. Here, we describe an improved wavelet-based technique that better characterizes ancestry block structure from observed genomic patterns. principal components analysis is first applied to genomic data to identify the primary population structure, followed by wavelet decomposition to develop a new characterization of local ancestry information along the chromosomes. For testing purposes, this method is applied to human genome-wide genotype data from Indonesia, as well as virtual genetic data generated using genome-scale sequential coalescent simulations under a wide range of admixture scenarios. Time of admixture is inferred using an approximate Bayesian computation framework, providing robust estimates of both admixture times and their associated levels of uncertainty. Crucially, we demonstrate that this revised wavelet approach, which we have released as the R package adwave, provides improved statistical power over existing wavelet-based techniques and can be used to address a broad range of admixture questions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.