SynthesisMolecular diagnosis & therapy2015
Latent tuberculosis infection screening in immigrants to low-incidence countries: a meta-analysis.
Synthesis in Molecular diagnosis & therapy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- [Recommendations for the screening for infectious diseases, mental health, and female genital mutilation in immigrant patients seen in Primary Care].Atencion primaria · 2020Guideline
- Effectiveness of interventions for reducing TB incidence in countries with low TB incidence: a systematic review of reviews.European respiratory review : an official journal of the European Respiratory Society · 2019Pooled it
- The effectiveness and cost-effectiveness of screening for latent tuberculosis among migrants in the EU/EEA: a systematic review.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2018Pooled it
- Comparison of QuantiFERON-TB Gold In-Tube (QFT-GIT) and tuberculin skin test (TST) for diagnosis of latent tuberculosis in haemodialysis (HD) patients: a meta-analysis of κ estimates.Epidemiology and infection · 2017Pooled it
- Long-term occupational risk of latent tuberculosis infection in Hamburg, Germany: Findings from a 13-year prospective observational study.Journal of clinical tuberculosis and other mycobacterial diseases · 2025Article
- Role of latent tuberculosis infection on elevated risk of cardiovascular disease: a population-based cohort study of immigrants in British Columbia, Canada, 1985-2019.Epidemiology and infection · 2023Article
- Article
- Comparison of three tests for latent tuberculosis infection in high-risk people in the USA: an observational cohort study.The Lancet. Infectious diseases · 2022Observational
- A Pilot TB Screening Model in a U.S. Prison Population Using Tuberculin Skin Test and Interferon Gamma Release Assay Based on Country of Origin.Journal of correctional health care : the official journal of the National Commission on Correctional Health Care · 2021Article
- Risk of active tuberculosis in migrants diagnosed with cancer: a retrospective cohort study in British Columbia, Canada.BMJ open · 2021Article
- Trend and treatment outcomes of latent tuberculosis infection among migrant persons in Japan: retrospective analysis of Japan tuberculosis surveillance data.BMC infectious diseases · 2021Article
- Cost-effectiveness of Latent Tuberculosis Infection Screening before Immigration to Low-Incidence Countries.Emerging infectious diseases · 2019Article
- Risk Factors for Indeterminate Outcome on Interferon Gamma Release Assay in Non-US-Born Persons Screened for Latent Tuberculosis Infection.Open forum infectious diseases · 2018Article
- Cost-effectiveness of post-landing latent tuberculosis infection control strategies in new migrants to Canada.PloS one · 2017Article
- Article
- The impact of migration on tuberculosis epidemiology and control in high-income countries: a review.BMC medicine · 2016Review
- A Step toward Tuberculosis Elimination in a Low-Incidence Country: Successful Diagnosis and Treatment of Latent Tuberculosis Infection in a Refugee Clinic.Canadian respiratory journal · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundImmigration from regions with a high incidence of tuberculosis (TB) has slowed the decline of TB in low-incidence regions. Targeted screening of new immigrants and treatment for latent TB infection (LTBI) is needed to reinvigorate this decline. This meta-analysis compares LTBI diagnostic tests by positive test prevalence and proportion of positive tests by TB incidence.
methodsA systematic literature search was performed and data extracted based on tuberculin skin test (TST) and/or interferon-gamma release assay (IGRA) use in immigrants. For the eight studies performing tests concurrently, data were compared by positive tests and concordance, while other studies comparing individual tests were analyzed based on demographic factors. Data were analyzed via meta-analysis.
resultsForty-five studies with a combined sample size of 93,249 individuals were included in the analyses, 2206 of which were from the eight concurrent studies. Odds of a positive TST were significantly higher than an IGRA (odds ratio 1.46; 95% confidence interval 1.07-2.01) and test agreement was moderate. Proportion of positive TST and IGRA tests increased with TB incidence, although not linearly.
conclusionTST and IGRA data relating to immigrants are lacking, especially long-term follow-up and comparative data. Further data are urgently needed to determine TB risks after immigration, long-term TB development, and treatment outcomes.
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