Evidence map›Paper›PMID 25850998›Full record

ArticleEpidemiology and infection2015

Is cystic echinoccocosis re-emerging in western Spain?

A Lopez-Bernus, M Belhassen-García, A Carpio-Perez, L Perez Del Villar, A Romero-Alegria, V Velasco-Tirado, A Muro, J Pardo-Lledias, M Cordero-Sánchez, M Alonso-Sardón

Open access · bronzeAbstract read
In one paragraph

Article in Epidemiology and infection, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. A Comprehensive Analysis ofPathogens (Basel, Switzerland) · 2025
    Review
  4. Article
  5. Article
  6. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

A Lopez-BernusServicio de Medicina Interna,Complejo Asistencial Universitario de Salamanca (CAUSA),Instituto Biosanitario de Salamanca (IBSAL),Salamanca,Spain.
M Belhassen-GarcíaServicio de Medicina Interna,Complejo Asistencial Universitario de Salamanca (CAUSA),Instituto Biosanitario de Salamanca (IBSAL),Salamanca,Spain.
A Carpio-PerezServicio de Medicina Interna,Complejo Asistencial Universitario de Salamanca (CAUSA),Instituto Biosanitario de Salamanca (IBSAL),Salamanca,Spain.
L Perez Del VillarCentro de Investigación de Enfermedades Tropicales de la Universidad de Salamanca (CIETUS),IBSAL,Salamanca,Spain.
A Romero-AlegriaServicio de Medicina Interna,Complejo Asistencial Universitario de Salamanca (CAUSA),Instituto Biosanitario de Salamanca (IBSAL),Salamanca,Spain.
V Velasco-TiradoServicio de Medicina Interna,Complejo Asistencial Universitario de Salamanca (CAUSA),Instituto Biosanitario de Salamanca (IBSAL),Salamanca,Spain.
A MuroCentro de Investigación de Enfermedades Tropicales de la Universidad de Salamanca (CIETUS),IBSAL,Salamanca,Spain.
J Pardo-LlediasServicio de Medicina Interna,Hospital General de Palencia 'Río Carrión',Palencia,Spain.
M Cordero-SánchezServicio de Medicina Interna,Complejo Asistencial Universitario de Salamanca (CAUSA),Instituto Biosanitario de Salamanca (IBSAL),Salamanca,Spain.
M Alonso-SardónDepartamento de Medicina Preventiva,Salud Publica y Microbiologia Medica.Universidad de Salamanca,Salamanca,Spain.
Complejo Hospitalario de Salamanca · ESInstituto de Investigación Biomédica de Salamanca · ESUniversidad de Salamanca · ESHospital Rio Carrion · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cystic echinococcosis (CE) remains an important health problem in many areas of the world, including the Mediterranean region. We performed a retrospective study of cases reported from 1998 to 2012 in order to review and update the epidemiology of this disease in a highly endemic area situated in western Spain. A total of 471 patients were diagnosed with hydatid disease. Of these cases, 55·8% were male, with an average age of 62·3 ± 19·5 years. More importantly, 1·5% of patients were children, and 20·5% were aged <45 years. An active therapeutic approach was implemented for 92·6% of the CE patients with primary diagnoses; however, a 'watch and wait' strategy was used in 59·3% of all secondary CE diagnoses. The incidence rate of hydatid disease was significantly higher compared to the incidence described in the Notifiable Disease System in this area. Furthermore, a significant decrease in hydatid incidence during the years included in the study was observed (β = -0·4357, P < 0·001). CE incidence has diminished in recent years, although active transmission remains in paediatric cases. Additionally, CE incidence remains high in our region despite public health plans for its control. The documented incidence of CE disease clearly underestimates the real numbers.

Indexed as

AdolescentAdultAgedAged, 80 and overBone Diseases, InfectiousChildChild, PreschoolCohort StudiesCommunicable Diseases, EmergingEchinococcosisEchinococcosis, HepaticEchinococcosis, PulmonaryFemaleHumansIncidenceInfantEchinococcusemerging infectionshydatid diseaseinfectious disease epidemiologyzoonoses

Identifiers

PMID25850998
PMCPMC9150940
OpenAlexW2131411985

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.