Evidence map›Paper›PMID 25850995›Full record

ReviewTransplant infectious disease : an official journal of the Transplantation Society2015

Conservative management of neurocysticercosis in a patient with hematopoietic stem cell transplantation: a case report and review.

S Purvey, K Lu, S K Mukkamalla, P Anandi, B Dumitriu, S Kranick, D A Hammoud, E O'Connell, A L Oh, J Barrett and 2 more

Open access · bronzeAbstract readCase ReportsReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Transplant infectious disease : an official journal of the Transplantation Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 1 country.

S PurveyHematology Branch, National Heart, Lung, Blood Institute, National Institutes of Health (NIH), Bethesda, Maryland, USA.
K LuHematology Branch, National Heart, Lung, Blood Institute, National Institutes of Health (NIH), Bethesda, Maryland, USA.
S K MukkamallaHematology Branch, National Heart, Lung, Blood Institute, National Institutes of Health (NIH), Bethesda, Maryland, USA.
P AnandiHematology Branch, National Heart, Lung, Blood Institute, National Institutes of Health (NIH), Bethesda, Maryland, USA.
B DumitriuHematology Branch, National Heart, Lung, Blood Institute, National Institutes of Health (NIH), Bethesda, Maryland, USA.
S KranickNational Institute of Neurological Disorders and Stroke, NIH, Bethesda, Maryland, USA.
D A HammoudCenter for Infectious Disease Imaging (CIDI), Radiology and Imaging Sciences, Clinical Center, NIH, Bethesda, Maryland, USA.
E O'ConnellNational Institute of Allergy and Infectious Diseases, NIH, Bethesda, Maryland, USA.
A L OhUniversity of Illinois at Chicago, Chicago, Illinois, USA.
J BarrettHematology Branch, National Heart, Lung, Blood Institute, National Institutes of Health (NIH), Bethesda, Maryland, USA.
S MahantyNational Institute of Allergy and Infectious Diseases, NIH, Bethesda, Maryland, USA.
M BattiwallaHematology Branch, National Heart, Lung, Blood Institute, National Institutes of Health (NIH), Bethesda, Maryland, USA.
National Heart Lung and Blood Institute · USNational Institutes of Health · USNational Institute of Allergy and Infectious Diseases · USNational Institute of Neurological Disorders and Stroke · USNational Institutes of Health Clinical Center · USUniversity of Illinois Chicago · US

Funding

Intramural NIH HHS Z99 HL999999
6 · The paper itself

Abstract

Neurocysticercosis, an infection of the central nervous system with the larval stage of the cestode Taenia solium, is common in developing countries but its occurrence and management in allogeneic hematopoietic stem cell transplantation (HSCT) has not been reported previously, to our knowledge. We report the case of an immigrant female patient who underwent a matched-related allogeneic HSCT for acute lymphoblastic leukemia and was incidentally found to have a solitary viable neurocysticercosis lesion. However, despite severe immunosuppression, the size of the cyst did not increase. More importantly, restoration of the immune system did not induce significant inflammation or seizures. Subsequent follow-up demonstrated complete resolution of the neurocysticercosis lesion. Thus, in the setting of HSCT, an asymptomatic patient with a single neurocysticercosis lesion was successfully managed without the use of anthelmintics, steroids, or anti-epileptics.

Indexed as

AdultCystsFemaleHematopoietic Stem Cell TransplantationHumansImmunosuppression TherapyNeurocysticercosisPrecursor Cell Lymphoblastic Leukemia-LymphomaTransplantation, Homologousallogeneic hematopoietic stem cell transplantationanthelminticsneurocysticercosisparasiteTaenia soliumtapeworm

Identifiers

PMID25850995
PMCPMC4464908
OpenAlexW1970400409

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.