Trial reportEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2015
Anterior cervical interbody fusion with the Zero-P spacer: mid-term results of two-level fusion.
Trial report in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 50 citations in OpenAlex.
- Zero-profile anchored spacer versus conventional plate-cage construct in bilevel anterior cervical discectomy and fusion: a systematic review and meta-analysis.Journal of orthopaedic surgery and research · 2023Pooled it
- Changes in cervical alignment of Zero-profile device versus conventional cage-plate construct after anterior cervical discectomy and fusion: a meta-analysis.Journal of orthopaedic surgery and research · 2022Pooled it
- Incidence of dysphagia of zero-profile spacer versus cage-plate after anterior cervical discectomy and fusion: A meta-analysis.Medicine · 2019Pooled it
- Biportal Endoscopic Surgery With Trans-Pedicle Approach Treat Central Cervical Disc Herniation: A Keyhole Technique With Assisting Portals.Clinical spine surgery · 2026Article
- Anterior Cervical Discectomy and Fusion with Polyetheretherketone Cage or Anterior Cervical Plate: A Comparative Evaluation of Short-term Outcomes.Journal of orthopaedic case reports · 2026Article
- Article
- Anterior cervical discectomy and fusion with a zero-profile VA spacer device: a clinical and radiological study with two-year follow-up.Journal of orthopaedic surgery and research · 2024Article
- Mechanical properties of an elastically deformable cervical spine implant.Journal of orthopaedic surgery and research · 2023Article
- Outcomes of different zero-profile spacers in the treatment of two-level cervical degenerative disk disease.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023Article
- Biomechanical effect of endplate defects on the intermediate vertebral bone in consecutive two-level anterior cervical discectomy and fusion: a finite element analysis.BMC musculoskeletal disorders · 2023Article
- Biomechanical performance of the novel assembled uncovertebral joint fusion cage in single-level anterior cervical discectomy and fusion: A finite element analysis.Frontiers in bioengineering and biotechnology · 2023Article
- Article
- The Correlation between Cervical Fusion Length and Functional Outcomes in Patients with Traumatic Spinal Cord Damage-A Registry-Based Cohort Study.Journal of clinical medicine · 2022Article
- Review
- Comparing the Bridge-Type Zero-Profile Anchored Spacer (ROI-C) Interbody Fusion Cage System and Anterior Cervical Discectomy and Fusion (ACDF) with Plating and Cage System in Cervical Spondylotic Myelopathy.Orthopaedic surgery · 2022Article
- Application of a new integrated low-profile anterior plate and cage system in single-level cervical spondylosis: a preliminary retrospective study.Journal of orthopaedic surgery and research · 2022Article
- Expert's comment concerning Grand Rounds case entitled "Vertebral body fracture after anterior cervical discectomy and fusion with zero-profile anchored cages in adjacent levels: a cautionary tale" by Mattei TA, Teles AR, Dinh DH (Eur Spine J [2016] doi:10.1007/s00586-015-4358-39).European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2020Article
- Article
- Radiological Fusion Criteria of Postoperative Anterior Cervical Discectomy and Fusion: A Systematic Review.Global spine journal · 2018Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeOur aim was to compare the safety and efficacy of anterior cervical discectomy and fusion (ACDF) using the Zero-P spacer versus the plate method in patients with cervical spine spondylosis.
methodsClinical and radiologic data from 69 patients undergoing two-level ACDF from January 2009 to May 2011 were collected prospectively. The Zero-P spacer was implanted in 37 patients (group A) and the anterior cervical plate and interbody cage in 32 (group B). Patients were followed for at least 3 years after surgery. Clinical outcomes were analyzed using the Neck Disability Index and Japanese Orthopaedic Association (JOA) scoring. The thickness of the prevertebral soft tissue at the fused levels was measured on the lateral cervical spine radiographs and dysphagia was assessed using the Bazaz score. Fusion rate, change in cervical lordosis, and adjacent segment degeneration were analyzed.
resultsNeurologic outcomes were statistically equivalent between the two groups. The incidence of postoperative dysphagia was significantly lower in group A than in group B at 2 and 6 months (p < 0.05). At the final follow-up, there were no significant differences in the C2-C7 Cobb angles between the two groups (p > 0.05). Also, degenerative changes in adjacent segments occurred in five group A patients and seven group B patients (p = 0.361). There were no differences in fusion rate during the radiologic follow-up.
conclusionsClinical results with the Zero-P spacer used for two-level ACDF were satisfactory. The device is superior to the traditional plate for preventing postoperative dysphagia and avoiding possible complications associated with a plate. Prospective trials with more patients and longer follow-ups are required to confirm these observations.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.