ArticleNature biotechnology2015
Silence on the relevant literature and errors in implementation.
Abstract readLetterComment
In one paragraph
Article in Nature biotechnology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- Cell State Transition Models Stratify Breast Cancer Cell Phenotypes and Reveal New Therapeutic Targets.Cancers · 2024Article
- Reversing pathological cell states: the road less travelled can extend the therapeutic horizon.Trends in cell biology · 2023Review
- Control of cell state transitions.Nature · 2022Article
- A systematic analysis of signaling reactivation and drug resistance.Cell reports · 2021Article
- Mapping connections in signaling networks with ambiguous modularity.NPJ systems biology and applications · 2019Article
- Fitting mathematical models of biochemical pathways to steady state perturbation response data without simulating perturbation experiments.Scientific reports · 2018Article
- Experimental noise cutoff boosts inferability of transcriptional networks in large-scale gene-deletion studies.Nature communications · 2018Article
- Netter: re-ranking gene network inference predictions using structural network properties.BMC bioinformatics · 2016Article
- Response to letter of correspondence - Bastiaens et al.Nature biotechnology · 2015Article
Corrections and comments
- Commented on by
- Comment on
Authors and funding
18 authors.
Philippe BastiaensDepartment of Systemic Cell Biology, Max Planck Institute of Molecular Physiology, Dortmund, Germany.
Marc R BirtwistleIcahn School of Medicine at Mount Sinai, Dept. of Pharmacology and Systems Therapeutics, New York, New York, USA.
Nils Blüthgen1] Institut für Pathologie Charite, Universitätsmedizin Berlin, Campus Mitte, Berlin, Germany. [2] Integrative Research Institute for the Life Sciences, Humboldt University Berlin, Berlin, Germany.
Frank J BruggemanSystems Bioinformatics, VU University, Amsterdam, The Netherlands.
Kwang-Hyun ChoDepartment of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology (KAIST), Yuseong-gu, Daejeon, Republic of Korea.
Carlo CosentinoDepartment of Experimental and Clinical Medicine, Magna Graecia University of Catanzaro, Campus Salvatore Venuta, Catanzaro, Italy.ORCID 0000000157681829
Alberto de la FuenteDepartment of Biomathematics and Bioinformatics, Institute for Genetics and Biometry, Leibniz Institute for Farm Animal Biology, Dummerstorf, Mecklenburg-Vorpommern, Germany.
Jan B HoekDepartment of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Anatoly KiyatkinDepartment of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000000250606081
Steffen KlamtMax Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany.
Walter Kolch1] Systems Biology Ireland, University College Dublin, Belfield, Dublin, Ireland. [2] Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin, Ireland. [3] School of Medicine and Medical Science, University College Dublin, Belfield, Dublin, Ireland.ORCID 0000000157775016
Stefan LegewieInstitute of Molecular Biology (IMB), Mainz, Germany.
Pedro Mendes1] Manchester Centre for Integrative Systems Biology, Manchester Institute of Biotechnology, The University of Manchester, Manchester, UK. [2] School of Computer Science, Manchester Institute of Biotechnology, The University of Manchester, Manchester, UK. [3] Center for Quantitative Medicine, University of Connecticut Health Center, Farmington, Connecticut, USA.ORCID 0000000165079168
Takashi NakaFaculty of Information Science, Kyushu Sangyo University, Higashi-ku, Fukuoka, Japan.
Tapesh SantraSystems Biology Ireland, University College Dublin, Belfield, Dublin, Ireland.
Eduardo SontagDepartment of Mathematics and Cancer Institute of New Jersey, Rutgers University, Piscataway, New Jersey, USA.
Hans V Westerhoff1] Manchester Centre for Integrative Systems Biology, Manchester Institute of Biotechnology, The University of Manchester, Manchester, UK. [2] Molecular Cell Physiology, VU University, Amsterdam, The Netherlands. [3] Synthetic Systems Biology, Swammerdam Institute for Life Sciences, Faculty of Science, University of Amsterdam, Amsterdam, The Netherlands.
Boris N Kholodenko1] Systems Biology Ireland, University College Dublin, Belfield, Dublin, Ireland. [2] Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin, Ireland. [3] School of Medicine and Medical Science, University College Dublin, Belfield, Dublin, Ireland.
Funding
System Biology Center in New YorkP50GM071558 · NIGMS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI ZAPH, SUSANA NEVES · 2007 to 2017
$22.8MBiotechnology and Biological Sciences Research Council BB/C008219/1Biotechnology and Biological Sciences Research Council BB/F003528/1
Abstract
PubMed holds no abstract for this paper.
Indexed as
Gene Regulatory NetworksModels, Theoretical
Identifiers
PMID
25850052What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.