Evidence map›Paper›PMID 25849947›Full record

ArticleNutrients2015

Maternal dietary patterns during pregnancy in relation to offspring forearm fractures: prospective study from the Danish National Birth Cohort.

Sesilje B Petersen, Morten A Rasmussen, Sjurdur F Olsen, Peter Vestergaard, Christian Mølgaard, Thorhallur I Halldorsson, Marin Strøm

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 4 pooled it
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 4 syntheses or guidelines pooled it, 34 citations in OpenAlex.

  1. Pooled it
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  5. Review
  6. Birth weight and birth length affect future fracture risk differently in men and women.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2024
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  8. Early Life Programming of Skeletal Health.Current osteoporosis reports · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

Sesilje B PetersenCentre for Fetal Programming, Department of Epidemiology Research, Statens Serum Institute, 2300 Copenhagen, Denmark. ssp@ssi.dk.
Morten A RasmussenDepartment of Food Science, Faculty of Science, University of Copenhagen, 1958 Frederiksberg, Denmark. mortenr@food.ku.dk.
Sjurdur F OlsenCentre for Fetal Programming, Department of Epidemiology Research, Statens Serum Institute, 2300 Copenhagen, Denmark. sfo@ssi.dk.
Peter VestergaardDepartment of Endocrinology, Aalborg University Hospital, 9000 Aalborg, Denmark. p-vest@post4.tele.dk.
Christian MølgaardDepartment of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, 1958 Frederiksberg, Denmark. cm@nexs.ku.dk.
Thorhallur I HalldorssonCentre for Fetal Programming, Department of Epidemiology Research, Statens Serum Institute, 2300 Copenhagen, Denmark. lur@ssi.dk.
Marin StrømCentre for Fetal Programming, Department of Epidemiology Research, Statens Serum Institute, 2300 Copenhagen, Denmark. mrm@ssi.dk.
Copenhagen Business School · DKStatens Serum Institut · DKAalborg University Hospital · DKHarvard University · USUniversity of Iceland · IS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Limited evidence exists for an association between maternal diet during pregnancy and offspring bone health. In a prospective study, we examined the association between dietary patterns in mid-pregnancy and offspring forearm fractures. In total, 101,042 pregnancies were recruited to the Danish National Birth Cohort (DNBC) during 1996-2002. Maternal diet was collected by a food frequency questionnaire. Associations were analyzed between seven dietary patterns extracted by principal component analysis and offspring first occurrence of any forearm fracture diagnosis, extracted from the Danish National Patient Register, between time of birth and end of follow-up (< 16 year) (n = 53,922). In multivariable Cox regression models, offspring of mothers in the fourth vs. first quintile of the Western pattern had a significant increased risk (Hazard ratio, 95% confidence interval: 1.11, 1.01-1.23) of fractures, and there was a borderline significant positive trend (p = 0.06). The other dietary patterns showed no associations and neither did supplementary analyses of macro- and micronutrients or single food groups, except for the intake of artificially sweetened soft drinks, which was positively associated with offspring forearm fractures (p = 0.02). In the large prospective DNBC high mid-pregnancy consumption of Western diet and artificially sweetened soft drinks, respectively, indicated positive associations with offspring forearm fractures, which provides interesting hypotheses for future research.

Indexed as

DietMaternal Nutritional Physiological PhenomenaAdultBone and BonesCarbonated BeveragesDenmarkFemaleForearmFractures, BoneHumansMaleMicronutrientsMothersMotor ActivityMultivariate AnalysisNutrition AssessmentMicronutrients

Identifiers

PMID25849947
PMCPMC4425150
OpenAlexW2040798120

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.