ArticleBMC plant biology2015
Transcriptomic analysis of differentially expressed genes in an orange-pericarp mutant and wild type in pummelo (Citrus grandis).
Article in BMC plant biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 46 citations in OpenAlex.
- Integrated metabolomic and transcriptomic analysis of the mechanism underlying pericarp variegation inFrontiers in plant science · 2026Article
- A Study on the Cell Layer Patterns of a Citrus Periclinal Chimera Reveals β-Cryptoxanthin Regulation in Citrus Fruits.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
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- Metabolic Profiling and Transcriptional Analysis of Carotenoid Accumulation in a Red-Fleshed Mutant of Pummelo (Molecules (Basel, Switzerland) · 2022Article
- Genomic Approaches for Improvement of Tropical Fruits: Fruit Quality, Shelf Life and Nutrient Content.Genes · 2021Review
- Adaptive Responses ofInternational journal of molecular sciences · 2021Article
- Selection and Evaluation of a Thornless and HLB-Tolerant Bud-Sport of Pummelo Citrus With an Emphasis on Molecular Mechanisms.Frontiers in plant science · 2021Article
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- Identification and characterization of a novel stay-green QTL that increases yield in maize.Plant biotechnology journal · 2019Article
- IlluminaInternational journal of molecular sciences · 2019Article
- Transcriptome profiling reveals the roles of pigment mechanisms in postharvest broccoli yellowing.Horticulture research · 2019Article
- Comparative transcriptome and proteome profiling of two Citrus sinensis cultivars during fruit development and ripening.BMC genomics · 2017Article
- Root Adaptive Responses to Aluminum-Treatment Revealed by RNA-Seq in Two Citrus Species With Different Aluminum-Tolerance.Frontiers in plant science · 2017Article
- Omics studies of citrus, grape and rosaceae fruit trees.Breeding science · 2016Review
- Transcriptome Analysis of Differentially Expressed Genes Involved in Proanthocyanidin Accumulation in the Rhizomes of Fagopyrum dibotrys and an Irradiation-Induced Mutant.Frontiers in physiology · 2016Article
- Comparative Transcriptomic Analyses of Vegetable and Grain Pea (Pisum sativum L.) Seed Development.Frontiers in plant science · 2015Article
- Transcriptome profiling reveals differential gene expression in proanthocyanidin biosynthesis associated with red/green skin color mutant of pear (Pyrus communis L.).Frontiers in plant science · 2015Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe external colour of fruit is a crucial quality feature, and the external coloration of most citrus fruits is due to the accumulation of carotenoids. The molecular regulation of carotenoid biosynthesis and accumulation in pericarp is limited due to the lack of mutant. In this work, an orange-pericarp mutant (MT) which showed altered pigmentation in the pericarp was used to identify genes potentially related to the regulation of carotenoid accumulation in the pericarp.
resultsHigh Performance Liquid Chromatography (HPLC) analysis revealed that the pericarp from MT fruits had a 10.5-fold increase of β-carotene content over that of the Wild Type (WT). Quantitative real-time PCR (qRT-PCR) analysis showed that the expression of all downstream carotenogenic genes was lower in MT than in WT, suggesting that down-regulation is critical for the β-carotene increase in the MT pericarp. RNA-seq analysis of the transcriptome revealed extensive changes in the MT gene expression level, with 168 genes down-regulated and 135 genes up-regulated. Gene ontology (GO) and KEGG pathway analyses indicated seven reliable metabolic pathways are altered in the mutant, including carbon metabolism, starch and sucrose metabolism and biosynthesis of amino acids. The transcription factors and genes corresponding to effected metabolic pathways may involved in the carotenoid regulation was confirmed by the qRT-PCR analysis in the MT pericarp.
conclusionsThis study has provided a global picture of the gene expression changes in a novel mutant with distinct color in the fruit pericarp of pummelo. Interpretation of differentially expressed genes (DEGs) revealed new insight into the molecular regulation of β-carotene accumulation in the MT pericarp.
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