ArticlePloS one2015
Social functioning trajectories of young first-episode psychosis patients with and without cannabis misuse: a 30-month follow-up study.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 4 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 4 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- Measures of Social and Occupational Function in Early Psychosis: A Systematic Review and Meta-analysis.Schizophrenia bulletin · 2024Pooled it
- Psychological interventions for psychosis in adolescents.The Cochrane database of systematic reviews · 2020Pooled it
- Psychosocial interventions for people with both severe mental illness and substance misuse.The Cochrane database of systematic reviews · 2019Pooled it
- Social Functioning Interventions in Psychosis: A Systematic Review.Clinical psychology & psychotherapyPooled it
- Randomized Laboratory Study of Single-Dose Cannabis, Dronabinol, and Placebo in Patients With Schizophrenia and Cannabis Use Disorder.Schizophrenia bulletin · 2025Trial
- Cognitive Behavioral Therapy Program for Cannabis Use Cessation in First-Episode Psychosis Patients: A 1-Year Randomized Controlled Trial.International journal of environmental research and public health · 2022Trial
- Trial
- People with psychotic disorders are the most vulnerable to cannabis adverse health outcomes: a study in WA State, USA.Community mental health journal · 2026Article
- The relationship between substance use and self-reported aspects of social functioning in patients with a psychotic disorder.European psychiatry : the journal of the Association of European Psychiatrists · 2024Article
- Understanding Lifelong Factors and Prediction Models of Social Functioning After Psychosis Onset Using the Large-Scale GROUP Cohort Study.Schizophrenia bulletin · 2023Article
- Provider Intentions to Implement Cannabis Use Intervention in First Episode Psychosis Treatment.Community mental health journal · 2023Article
- Understanding the complexity, patterns, and correlates of alcohol and other substance use among young people seeking help for mental ill-health.Social psychiatry and psychiatric epidemiology · 2023Article
- Premorbid Adjustment and IQ in Patients With First-Episode Psychosis: A Multisite Case-Control Study of Their Relationship With Cannabis Use.Schizophrenia bulletin · 2020Article
- Cognitive Analytic Therapy for psychosis: A case series.Psychology and psychotherapy · 2019Article
- Cannabis acute use impacts symptoms and functionality in a cohort of antipsychotic naïve First Episode of Psychosis individuals.Schizophrenia research. Cognition · 2019Article
- McLean OnTrack: a transdiagnostic program for early intervention in first-episode psychosis.Early intervention in psychiatry · 2017Article
Corrections and comments
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Authors and funding
6 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of the study was to investigate trajectories of social functioning in young people with first-episode psychosis (FEP) with and without cannabis misuse using a secondary analysis of data from the Episode-II trial. Forty-two young people with FEP and comorbid cannabis use disorder were compared with 39 young people with FEP but without a cannabis use disorder. Social functioning was assessed every 6 months during a 30-month follow-up. Multilevel linear growth curve modeling was used to compare the social functioning trajectories over time for those with and without cannabis misuse. Cannabis misuse was not associated with social functioning at baseline assessment. Over a 30-month follow-up, FEP patients without cannabis disorder showed significant improvements in their social functioning, whereas patients with cannabis misuse at baseline displayed no such improvement. Patients with and without cannabis misuse differed significantly in their levels of social functioning after 24 months. Similar results were obtained after adjusting for potential confounders (i.e., age, gender, negative symptoms, premorbid functioning, DSM-IV diagnoses, baseline social functioning and other substance use). In the context of a specialized early intervention service, patients with cannabis misuse at baseline did not attain the improvements in social outcomes observed in their counterparts without cannabis misuse. There is a need to develop effective interventions to reduce cannabis misuse to ultimately improve social outcomes in young people with psychosis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.