Evidence map›Paper›PMID 25849563›Full record

ArticlePloS one2015

CHADS2 and CHA2DS2-VASc scoring systems for predicting atrial fibrillation following cardiac valve surgery.

Liang Yin, Xinyu Ling, Yufeng Zhang, Hua Shen, Jie Min, Wang Xi, Jing Wang, Zhinong Wang

Abstract read
In one paragraph

Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
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  6. Review
  7. The CHALife (Basel, Switzerland) · 2023
    Article
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  9. Article
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  12. Observational
  13. Article
  14. CHADSJournal of atherosclerosis and thrombosis · 2017
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Liang YinDepartment of Cardiothoracic Surgery, Changzheng Hospital, Second Military Medical University, Shanghai, 200003, China.
Xinyu LingDepartment of Cardiothoracic Surgery, Changzheng Hospital, Second Military Medical University, Shanghai, 200003, China.
Yufeng ZhangDepartment of Cardiothoracic Surgery, Changzheng Hospital, Second Military Medical University, Shanghai, 200003, China.
Hua ShenDepartment of Cardiothoracic Surgery, Changzheng Hospital, Second Military Medical University, Shanghai, 200003, China.
Jie MinDepartment of Cardiothoracic Surgery, Changzheng Hospital, Second Military Medical University, Shanghai, 200003, China.
Wang XiDepartment of Cardiothoracic Surgery, Changzheng Hospital, Second Military Medical University, Shanghai, 200003, China.
Jing WangDepartment of Cardiothoracic Surgery, Changzheng Hospital, Second Military Medical University, Shanghai, 200003, China.
Zhinong WangDepartment of Cardiothoracic Surgery, Changzheng Hospital, Second Military Medical University, Shanghai, 200003, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveClinical use of CHADS2 and CHA2DS2-VASc scoring systems for predicting AF following cardiac surgery have been reported in previous studies and demonstrated well-validated predictive value. We sought to investigate whether the two scoring systems are effective for predicting new-onset of AF following cardiac valve surgery and to demonstrate its potential utility of clinical assessment.

methodsMedical records of all patients underwent cardiac valve surgeries during the period of January 2003 and December 2013 without preoperative AF at the cardiac center of our university were reviewed. The main outcome end point of our study was the early new-onset of AF following cardiac valve surgery.

resultsThere were overall 518 patients involved in this study, with 234 (45.17%) developed POAF following valve surgery. Patients with POAF had older age (P=0.23) and higher BMI (P=0.013) than those without POAF. History of heart failure (P=0.025), hypertension (P=0.021), previous stroke or TIA (P=0.032), coronary artery disease (P=0.001), carotid artery disease (P=0.024) and preoperative medication of statins (P=0.021) were significantly more recorded in POAF group. Patients with POAF also had higher LAD (P=0.013) and E/e' ratio (P<0.001). The CHADS2 and CHA2DS2-VASc scores were significantly higher in patients with POAF (P=0.002; P<0.001), and under univariate and multivariate regression analysis the CHADS2 and CHA2DS2-VASc scores were significant predictors of POAF (P=0.001; P<0.001). Based on stratification of CHADS2 and CHA2DS2-VASc scores, the Kaplan-Meier analysis obtained a higher POAF rate on patients with higher stratification of CHADS2 and CHA2DS2-VASc scores (P<0.001; P<0.001).

conclusionIn conclusion, CHADS2 and CHA2DS2-VASc scores were directly associated with the incidence of POAF following valve surgery and a higher score was strongly predictive of POAF.

Indexed as

Models, StatisticalPostoperative ComplicationsAgedAtrial FibrillationCardiac Surgical ProceduresDecision Support TechniquesFemaleHeart DiseasesHeart ValvesHumansMaleMiddle AgedPatient SelectionPredictive Value of TestsRisk AssessmentRisk Factors

Identifiers

PMID25849563
PMCPMC4388656

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.