Evidence map›Paper›PMID 25849536›Full record

ArticlePloS one2015

A five-year prospective study of diabetic retinopathy progression in chinese type 2 diabetes patients with "well-controlled" blood glucose.

Peiyao Jin, Jinjuan Peng, Haidong Zou, Weiwei Wang, Jiong Fu, Binjie Shen, Xuelin Bai, Xun Xu, Xi Zhang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 26 citations in OpenAlex.

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  13. Frequency and Risk Factors for Neovascular Glaucoma After Vitrectomy in Eyes with Diabetic Retinopathy: An Observational Study.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Peiyao JinDepartment of Ophthalmology, Shanghai First People's Hospital, Shanghai Jiao Tong University, Shanghai, 20080, China.
Jinjuan PengDepartment of Ophthalmology, Shanghai First People's Hospital, Shanghai Jiao Tong University, Shanghai, 20080, China.
Haidong ZouDepartment of Ophthalmology, Shanghai First People's Hospital, Shanghai Jiao Tong University, Shanghai, 20080, China; Department of Preventative Ophthalmology, Shanghai Eye Disease Prevention and Treatment Center, Shanghai, 200040, China.
Weiwei WangBeixinjing Community Health Service Center, Shanghai, China.
Jiong FuBeixinjing Community Health Service Center, Shanghai, China.
Binjie ShenBeixinjing Community Health Service Center, Shanghai, China.
Xuelin BaiBeixinjing Community Health Service Center, Shanghai, China.
Xun XuDepartment of Ophthalmology, Shanghai First People's Hospital, Shanghai Jiao Tong University, Shanghai, 20080, China.
Xi ZhangDepartment of Ophthalmology, Shanghai First People's Hospital, Shanghai Jiao Tong University, Shanghai, 20080, China.
Shanghai Medical Information Center · CNShanghai First People's Hospital · CNShanghai Jiao Tong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo determine the progression rate and risk factors for diabetic retinopathy (DR) in Chinese type 2 diabetic patients who have reached the target hemoglobin A1c (HbA1c) level recommended by the American Diabetes Association.

methodsThis was a 5-year community-based prospective study. The study population consisted of patients with type 2 diabetes with HbA1c less than 7.0%. Demographic information, systemic examination results and ophthalmological test results for each participant were collected. The outcome of this study was the progression of DR, which was defined as an increase in DR grade in one or both eyes at the final visit in comparison to the baseline status. The association between each potential risk factor and DR progression was studied.

resultsA total of 453 patients with HbA1c less than 7.0% were included in the study group. In 146 patients (32.22%), DR developed or progressed during the five-year follow-up. Baseline HbA1c level was the only independent risk factor for DR progression (p<0.01, OR = 2.84, 95%CI: 2.11~3.82). The logistic regression function suggested that the possibility of DR progression increased fastest when baseline HbA1c increased from 5.2% to 6.4%. The 5-year DR progression rate in patients with baseline HbA1c less than 5.2%, between 5.2% and 6.4%, and over 6.4% were 19.62%, 24.41%, and 76.83%, respectively.

conclusionsTo slow the progression of DR in Chinese patients with type 2 diabetes, more intensive glucose control is recommended.

Indexed as

AdolescentAdultAgedAged, 80 and overBlood GlucoseChildDiabetes Mellitus, Type 2Diabetic RetinopathyDisease ProgressionFemaleFollow-Up StudiesGlycated HemoglobinHumansMaleMiddle AgedPrognosisBlood GlucoseGlycated Hemoglobin

Identifiers

PMID25849536
PMCPMC4388440
OpenAlexW2042703173

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.