Evidence map›Paper›PMID 25849076›Full record

ArticlePloS one2015

A nontoxic polypeptide oligomer with a fungicide potency under agricultural conditions which is equal or greater than that of their chemical counterparts.

Sara Monteiro, Alexandra Carreira, Regina Freitas, Ana Margarida Pinheiro, Ricardo Boavida Ferreira

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Article
  3. International journal of molecular sciences · 2021
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Narrow-Leafed Lupin (Frontiers in plant science · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Sara MonteiroCentro de Botânica Aplicada à Agricultura, Instituto Superior de Agronomia, Universidade de Lisboa, Lisboa, Portugal; Converde, SA, Biocant-Park, Cantanhede, Portugal.
Alexandra CarreiraConverde, SA, Biocant-Park, Cantanhede, Portugal.
Regina FreitasCentro de Botânica Aplicada à Agricultura, Instituto Superior de Agronomia, Universidade de Lisboa, Lisboa, Portugal.
Ana Margarida PinheiroCentro de Botânica Aplicada à Agricultura, Instituto Superior de Agronomia, Universidade de Lisboa, Lisboa, Portugal.
Ricardo Boavida FerreiraCentro de Botânica Aplicada à Agricultura, Instituto Superior de Agronomia, Universidade de Lisboa, Lisboa, Portugal; Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Oeiras, Portugal.
University of Lisbon · PTBiocant · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There are literally hundreds of polypeptides described in the literature which exhibit fungicide activity. Tens of them have had attempted protection by patent applications but none, as far as we are aware, have found application under real agricultural conditions. The reasons behind may be multiple where the sensitivity to the Sun UV radiation can come in first place. Here we describe a multifunctional glyco-oligomer with 210 kDa which is mainly composed by a 20 kDa polypeptide termed Blad that has been previously shown to be a stable intermediary product of β-conglutin catabolism. This oligomer accumulates exclusively in the cotyledons of Lupinus species, between days 4 and 12 after the onset of germination. Blad-oligomer reveals a plethora of biochemical properties, like lectin and catalytic activities, which are not unusual per si, but are remarkable when found to coexist in the same protein molecule. With this vast range of chemical characteristics, antifungal activity arises almost as a natural consequence. The biological significance and potential technological applications of Blad-oligomer as a plant fungicide to agriculture, its uniqueness stems from being of polypeptidic in nature, and with efficacies which are either equal or greater than the top fungicides currently in the market are addressed.

Indexed as

AgricultureProtein MultimerizationAnimalsBeesChitinFungiFungicides, IndustrialLupinusMicrobial Sensitivity TestsPeptidesChitinFungicides, IndustrialPeptides

Identifiers

PMID25849076
PMCPMC4388547
OpenAlexW2009028969

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.