Evidence map›Paper›PMID 25848800›Full record

ArticlePloS one2015

Unlocking patients with mental disorders who were in restraints at home: a national follow-up study of China's new public mental health initiatives.

Lili Guan, Jin Liu, Xia Min Wu, Dafang Chen, Xun Wang, Ning Ma, Yan Wang, Byron Good, Hong Ma, Xin Yu and 1 more

Abstract read
In one paragraph

Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Article
  2. Article
  3. From Chains to Care: EndingClinical practice and epidemiology in mental health : CP & EMH · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Transcultural psychiatry · 2023
    Article
  8. Indonesia free from pasung: a policy analysis.International journal of mental health systems · 2023
    Article
  9. Article
  10. Psychiatric diagnosis and treatment in the 21st century: paradigm shifts or power shifts?World psychiatry : official journal of the World Psychiatric Association (WPA) · 2022
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Reducing coercion in mental healthcare.Epidemiology and psychiatric sciences · 2019
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lili GuanPeking University Sixth Hospital, Peking University Institute of Mental Health, Key Laboratory of Mental Health, Ministry of Health (Peking University), Beijing, China.
Jin LiuPeking University Sixth Hospital, Peking University Institute of Mental Health, Key Laboratory of Mental Health, Ministry of Health (Peking University), Beijing, China.
Xia Min WuPeking University Sixth Hospital, Peking University Institute of Mental Health, Key Laboratory of Mental Health, Ministry of Health (Peking University), Beijing, China.
Dafang ChenSchool of Public Health, Peking University, Beijing, China.
Xun WangPeking University Sixth Hospital, Peking University Institute of Mental Health, Key Laboratory of Mental Health, Ministry of Health (Peking University), Beijing, China.
Ning MaPeking University Sixth Hospital, Peking University Institute of Mental Health, Key Laboratory of Mental Health, Ministry of Health (Peking University), Beijing, China.
Yan WangSchool of Public Health, Peking University, Beijing, China.
Byron GoodDepartment of Global Health and Social Medicine, Harvard Medical School, Boston, Massachusetts, United States of America.
Hong MaPeking University Sixth Hospital, Peking University Institute of Mental Health, Key Laboratory of Mental Health, Ministry of Health (Peking University), Beijing, China.
Xin YuPeking University Sixth Hospital, Peking University Institute of Mental Health, Key Laboratory of Mental Health, Ministry of Health (Peking University), Beijing, China.
Mary-Jo GoodDepartment of Global Health and Social Medicine, Harvard Medical School, Boston, Massachusetts, United States of America.

Funding

Building Research Capacity to Improve Mental Health in China across the LifespanD43TW009081 · FIC · HARVARD MEDICAL SCHOOL · PI GOOD, BYRON J., GOOD, MARY-JO DELVECCHIO · 2011 to 2015
$1.2M
FIC NIH HHS D43 TW009081FIC NIH HHS D43TW009081
6 · The paper itself

Abstract

backgroundIn 2005, China implemented a demonstration program known as "686" to scale-up nation-wide basic mental health services designed to improve access to evidence-based care and to promote human rights for people with severe mental disorders. As part of the 686 Program, teams "unlocked" and provided continuous mental health care to people with severe mental disorders who were found in restraints and largely untreated in their family homes. We implemented a nation-wide two-stage follow-up study to measure the effectiveness and sustainability of the "unlocking and treatment" intervention and its impact on the well-being of patients' families.

methods266 patients unlocked from 2005 in "686" demonstration sites across China were recruited in Stage One of the study in 2009. In 2012, 230 of the 266 cases were re-interviewed (the Stage Two study). Outcome measures included the patient medication adherence and social functioning, family burden ratings, and relocking rate. We utilized pre-post tests to analyze the changes over time following the unlocking efforts.

results96% of patients were diagnosed with schizophrenia. Prior to unlocking, their total time locked ranged from two weeks to 28 years, with 32% having been locked multiple times. The number of persons regularly taking medicines increased from one person at the time of unlocking to 74% in 2009 and 76% in 2012. Pre-post tests showed sustained improvement in patient social functioning and significant reductions in family burden. Over 92% of patients remained free of restraints in 2012.

conclusionPractice-based evidence from our study suggests an important model for protecting the human rights of people with mental disorders and keeping them free of restraints can be achieved by providing accessible, community based mental health services with continuity of care. China's "686" Program can inform similar efforts in low-resource settings where community locking of patients is practiced.

Indexed as

Community Mental Health ServicesMental HealthPatient RightsChinaFemaleHumansMaleSchizophrenia

Identifiers

PMID25848800
PMCPMC4388503

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.