ReviewWorld journal of hepatology2015
Cirrhotic cardiomyopathy: Implications for the perioperative management of liver transplant patients.
Review in World journal of hepatology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 60 citations in OpenAlex.
- Propofol prevents further prolongation of QT interval during liver transplantation.Scientific reports · 2022Trial
- Post-transplant atrial tachyarrhythmias: Epidemiology, mechanisms, outcomes, and management across solid organs.World journal of transplantation · 2026Review
- YKL-40: Revolutionizing cardiac risk prediction and therapy in liver transplantation.World journal of transplantation · 2025Article
- Cardiac Remodeling and Arrhythmic Burden in Pre-Transplant Cirrhotic Patients: Pathophysiological Mechanisms and Management Strategies.Biomedicines · 2025Review
- [Cirrhotic cardiomyopathy – Clinically fact or academic curiosity? Review. Part 3: treatment]Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina) · 2024Review
- Therapies for Cirrhotic Cardiomyopathy: Current Perspectives and Future Possibilities.International journal of molecular sciences · 2024Review
- Cardiac Syndromes in Liver Disease: A Clinical Conundrum.Journal of clinical and translational hepatology · 2023Review
- Subclinical cardiac abnormalities in children with biliary atresia correlate with outcomes after liver transplantation.Frontiers in pediatrics · 2023Article
- Severe Cardiovascular Complications Following Liver Transplantation in Patients With Iron Overload.JACC. Case reports · 2022Article
- Article
- The predictive value of revised diastolic dysfunction in outcomes of liver transplantation: A propensity score matching analysis.Frontiers in surgery · 2022Article
- What's New in Cirrhotic Cardiomyopathy?-Review Article.Journal of personalized medicine · 2021Review
- Diastolic Dysfunction Is a Predictor of Poor Survival in Patients with Decompensated Cirrhosis.International journal of hepatology · 2021Article
- Left ventricular diastolic dysfunction in liver transplantation: a stronger association with non-alcoholic steatohepatitis.Clinical and experimental hepatology · 2020Article
- Cardiovascular and Metabolic Consequences of Liver Transplantation: A Review.Medicina (Kaunas, Lithuania) · 2019Review
- Cirrhotic cardiomyopathy: the liver affects the heart.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2019Review
- B-type peptides to predict post-liver transplant mortality: systematic review and meta-analysis.Canadian liver journal · 2019Review
- In-hospital cardiovascular events after liver transplantation: predictors and long-term outcome.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2018Article
- Outcomes of abdominal surgery in patients with liver cirrhosis.World journal of gastroenterology · 2016Review
- Acute Kidney Injury in Patients with Cirrhosis.Journal of clinical and translational hepatology · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cirrhotic cardiomyopathy is a disease that has only recently been recognised as a definitive clinical entity. In the setting of liver cirrhosis, it is characterized by a blunted inotropic and chronotropic response to stress, impaired diastolic relaxation of the myocardium and prolongation of the QT interval in the absence of other known cardiac disease. A key pathological feature is the persistent over-activation of the sympathetic nervous system in cirrhosis, which leads to down-regulation and dysfunction of the β-adrenergic receptor. Diagnosis can be made using a combination of echocardiography (resting and stress), tissue Doppler imaging, cardiac magnetic resonance imaging, 12-lead electrocardiogram and measurement of biomarkers. There are significant implications of cirrhotic cardiomyopathy in a number of clinical situations in which there is an increased physiological demand, which can lead to acute cardiac decompensation and heart failure. Prior to transplantation there is an increased risk of hepatorenal syndrome, cardiac failure following transjugular intrahepatic portosystemic shunt insertion and increased risk of arrhythmias during acute gastrointestinal bleeding. Liver transplantation presents the greatest physiological challenge with a further risk of acute cardiac decompensation. Peri-operative management should involve appropriate choice of graft and minimization of large fluctuations in preload and afterload. The avoidance of cardiac failure during this period has important prognostic implications, as there is evidence to suggest a long-term resolution of the abnormalities in cirrhotic cardiomyopathy.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.