ArticleJournal of inflammation research2015
The effects of grounding (earthing) on inflammation, the immune response, wound healing, and prevention and treatment of chronic inflammatory and autoimmune diseases.
Article in Journal of inflammation research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05050812 (The Grounded Brain), which is not on this map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Grounded Brain: How Sleeping Grounded (Earthing) Affects Cognition and Personal Perceptions in Participants With Mild Cognitive Impairment Due to Alzheimer's Disease (MCI/AD)
Who cites it
26 citing papers in PubMed, 80 citations in OpenAlex.
- Review
- Earthing effects on mitochondrial function: ATP production and ROS generation.FEBS open bio · 2025Article
- Review
- Earthing as a Supportive Therapy for Post-Spinal Surgery Recovery.Journal of clinical medicine · 2025Article
- Anti-inflammatory effect of grounding mat on trimethyltin-induced neurotoxicity rats.Journal of exercise rehabilitation · 2025Article
- Biobased Nanomaterials: Pioneering Innovations for Biomedical Advancements.Pharmaceutical nanotechnology · 2025Review
- Effects of Barefoot Walking in Urban Forests on CRP, IFNγ, and Serotonin Levels.Healthcare (Basel, Switzerland) · 2024Article
- Effect of Earthing Mats on Sleep Quality in Rats.International journal of molecular sciences · 2024Article
- Piezoelectric and Triboelectric Nanogenerators for Enhanced Wound Healing.Biomimetics (Basel, Switzerland) · 2023Review
- Biomodulating healing after arthroscopic rotator cuff repair: the protocol of a randomised proof of concept trial (BIOHACK).BMJ open · 2023Article
- Fiat Lux: Light and Pedagogy for the 21st Century.Annals of neurosciences · 2023Article
- Is a return to nature a piece of the health puzzle?Biomedical journal · 2023Article
- Illnesses in technologically advanced societies due to lack of grounding (earthing).Biomedical journal · 2023Review
- Practical applications of grounding to support health.Biomedical journal · 2023Review
- Influence of electromagnetic fields on the circadian rhythm: Implications for human health and disease.Biomedical journal · 2023Review
- Down to earth - A new type of hygiene.Biomedical journal · 2023Article
- The Effect of Earthing Mat on Stress-Induced Anxiety-like Behavior and Neuroendocrine Changes in the Rat.Biomedicines · 2022Article
- Grounding the Body Improves Sleep Quality in Patients with Mild Alzheimer's Disease: A Pilot Study.Healthcare (Basel, Switzerland) · 2022Article
- The Impact of Grounding in Running Shoes on Indices of Performance in Elite Competitive Athletes.International journal of environmental research and public health · 2022Article
- Comparison of Clinical Effects of Ankle Rehabilitation Exercise Bare Foot or Wearing Shoes.Iranian journal of public health · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Multi-disciplinary research has revealed that electrically conductive contact of the human body with the surface of the Earth (grounding or earthing) produces intriguing effects on physiology and health. Such effects relate to inflammation, immune responses, wound healing, and prevention and treatment of chronic inflammatory and autoimmune diseases. The purpose of this report is two-fold: to 1) inform researchers about what appears to be a new perspective to the study of inflammation, and 2) alert researchers that the length of time and degree (resistance to ground) of grounding of experimental animals is an important but usually overlooked factor that can influence outcomes of studies of inflammation, wound healing, and tumorigenesis. Specifically, grounding an organism produces measurable differences in the concentrations of white blood cells, cytokines, and other molecules involved in the inflammatory response. We present several hypotheses to explain observed effects, based on current research results and our understanding of the electronic aspects of cell and tissue physiology, cell biology, biophysics, and biochemistry. An experimental injury to muscles, known as delayed onset muscle soreness, has been used to monitor the immune response under grounded versus ungrounded conditions. Grounding reduces pain and alters the numbers of circulating neutrophils and lymphocytes, and also affects various circulating chemical factors related to inflammation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.