Evidence map›Paper›PMID 25848246›Full record

SynthesisInternational journal of chronic obstructive pulmonary disease2015

Effectiveness of bronchoscopic lung volume reduction using unilateral endobronchial valve: a systematic review and meta-analysis.

Miyoung Choi, Worl Suk Lee, Min Lee, Kyeongman Jeon, Seungsoo Sheen, Sanghoon Jheon, Young Sam Kim

Open access · goldAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in International journal of chronic obstructive pulmonary disease, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

  1. Robotic-Assisted Bronchoscopy for Volume Reduction of Giant Emphysematous Bulla: A Case Report.International journal of chronic obstructive pulmonary disease · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Miyoung ChoiNational Evidence-Based Healthcare Collaborating Agency, Seoul, Republic of Korea.
Worl Suk LeeNational Evidence-Based Healthcare Collaborating Agency, Seoul, Republic of Korea.
Min LeeNational Evidence-Based Healthcare Collaborating Agency, Seoul, Republic of Korea.
Kyeongman JeonDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Seungsoo SheenDepartment of Pulmonary and Critical Care Medicine, Ajou University School of Medicine, Suwon, Republic of Korea.
Sanghoon JheonDepartment of Thoracic and Cardiovascular Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.
Young Sam KimDepartment of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
National Evidenc- based healthcare Collaborating Agency · KRAjou University · KRSeoul National University Bundang Hospital · KRSeverance Hospital · KRSungkyunkwan University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBronchoscopic lung volume reduction (BLVR) can be suggested as an alternative for surgical lung volume reduction surgery for severe emphysema patients. This article intends to evaluate by systematic review the safety and effectiveness of BLVR using a one-way endobronchial valve.

methodsA systematic search of electronic databases, including MEDLINE, EMBASE, and the Cochrane Library, as well as eight domestic databases up to December 2013, was performed. Two reviewers independently screened all references according to selection criteria. The Scottish Intercollegiate Guidelines Network criterion was used to assess quality of literature. Data from randomized controlled trials were combined and meta-analysis was performed.

resultsThis review included 15 studies. Forced expiratory volume in 1 second (FEV1) improved in the intervention group compared with the control group (mean difference [MD]=6.71, 95% confidence interval [CI]: 3.31-10.11). Six-minute walking distance (MD=15.66, 95% CI: 1.69-29.64) and cycle workload (MD=4.43, 95% CI: 1.80-7.07) also improved. In addition, St George's Respiratory Questionnaire score decreased (MD=4.29, 95% CI: -6.87 to -1.71) in the intervention group. In a subgroup analysis of patients with complete fissure, the FEV1 change from baseline was higher in the BLVR group than in the control group for both 6 months (MD=15.28, P<0.001) and 12 months (MD=17.65, P<0.001), whereas for patients with incomplete fissure, FEV1 and 6-minute walking distance showed no change. One-year follow-up randomized controlled trials reported deaths, although the cause of death was not related to BLVR. Respiratory failure and pneumothorax incidence rates were relatively higher in the BLVR group, but the difference was not significant.

conclusionBLVR may be an effective and safe procedure for the treatment of severe COPD patients with emphysema, based on existing studies.

Indexed as

BronchoscopyChi-Square DistributionExercise ToleranceForced Expiratory VolumeHumansLungPneumonectomyPulmonary Disease, Chronic ObstructivePulmonary EmphysemaRecovery of FunctionSeverity of Illness IndexTreatment Outcomebronchoscopic valve lung volume reductionendobronchial valvemeta-analysissystematic review

Identifiers

PMID25848246
PMCPMC4386802
OpenAlexW1969319313

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.