ArticleOecologia2015
The stress of growing old: sex- and season-specific effects of age on allostatic load in wild grey mouse lemurs.
Article in Oecologia, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 50 citations in OpenAlex.
- Nicotinamide riboside treatment enhances stress sensitivity and modulates hematological dynamics in aged mice.GeroScience · 2026Article
- Article
- Recovery through resistance? nesting urban female song sparrows (Frontiers in physiology · 2025Article
- Temporal dynamics in gastrointestinal helminth infections of sympatric mouse lemur species (International journal for parasitology. Parasites and wildlife · 2024Article
- Impact of Long-Term Dietary High Fat and Eicosapentaenoic Acid on Behavior and Hypothalamic-Pituitary-Adrenal Axis Activity in Amyloidogenic APPswe/PSEN1dE9 Mice.Neuroendocrinology · 2024Article
- Senescence and the stress axis: a constraint or a trade-off of reproduction in mammals with fast and slow life histories.Proceedings. Biological sciences · 2023Article
- Season-dependent impact of forage quality on stress in alpine chamois.Ecology and evolution · 2023Article
- The application of allostasis and allostatic load in animal species: A scoping review.PloS one · 2022Article
- Seasonal drivers of faecal glucocorticoid metabolite concentrations in an African strepsirrhine primate, the thick-tailed greater galago (Conservation physiology · 2021Article
- Wild chimpanzees exhibit humanlike aging of glucocorticoid regulation.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Faecal Glucocorticoid Metabolites and H/L Ratio are Related Markers of Stress in Semi-Captive Asian Timber Elephants.Animals : an open access journal from MDPI · 2020Article
- Faecal glucocorticoid metabolite profiles in diademed sifakas increase during seasonal fruit scarcity with interactive effects of age/sex class and habitat degradation.Conservation physiology · 2019Article
- Like mother, like daughter: heritability of female Richardson's ground squirrelCurrent zoology · 2018Article
- Age, state, environment, and season dependence of senescence in body mass.Ecology and evolution · 2018Article
- Evolution of sex-specific pace-of-life syndromes: genetic architecture and physiological mechanisms.Behavioral ecology and sociobiology · 2018Review
- Hair cortisol concentrations correlate negatively with survival in a wild primate population.BMC ecology · 2017Article
- Does habitat disturbance affect stress, body condition and parasitism in two sympatric lemurs?Conservation physiology · 2016Article
- Host sex and age influence endoparasite burdens in the gray mouse lemur.Frontiers in zoology · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic stress [i.e. long-term elevation of glucocorticoid (GC) levels] and aging have similar, negative effects on the functioning of an organism. Aged individuals' declining ability to regulate GC levels may therefore impair their ability to cope with stress, as found in humans. The coping of aged animals with long-term natural stressors is virtually unstudied, even though the ability to respond appropriately to stressors is likely integral to the reproduction and survival of wild animals. To assess the effect of age on coping with naturally fluctuating energetic demands, we measured stress hormone output via GC metabolites in faecal samples (fGCM) of wild grey mouse lemurs (Microcebus murinus) in different ecological seasons. Aged individuals were expected to exhibit elevated fGCM levels under energetically demanding conditions. In line with this prediction, we found a positive age effect in the dry season, when food and water availability are low and mating takes place, suggesting impaired coping of aged wild animals. The age effect was significantly stronger in females, the longer-lived sex. Body mass of males but not females correlated positively with fGCM in the dry season. Age or body mass did not influence fGCM significantly in the rainy season. The sex- and season-specific predictors of fGCM may reflect the differential investment of males and females into reproduction and longevity. A review of prior research indicates contradictory aging patterns in GC regulation across and even within species. The context of sampling may influence the likelihood of detecting senescent declines in GC functioning.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.