ArticleBirth defects research. Part A, Clinical and molecular teratology2015
Next steps for birth defects research and prevention: The birth defects study to evaluate pregnancy exposures (BD-STEPS).
Article in Birth defects research. Part A, Clinical and molecular teratology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Maternal Smoking and Preterm Birth Among Infants With Orofacial Clefts.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2026Article
- Timing of Critical Congenital Heart Defect Detection: A Multisite Population-Based Study.The Journal of pediatrics · 2026Article
- Maternal Folic Acid Supplement Use, Folate Intake, and Preterm Birth Among Infants With Spina Bifida.Birth defects research · 2025Article
- Article
- Maternal exposure to zolpidem and risk of specific birth defects.Journal of sleep research · 2024Article
- Maternal physical activity, sitting, and risk of non-cardiac birth defects.Pediatric research · 2024Article
- Patterns of Prescription Medication Use during the First Trimester of Pregnancy in the United States, 1997-2018.Clinical pharmacology and therapeutics · 2023Article
- Maternal cyclobenzaprine exposure and risk of birth defects in the National Birth Defects Prevention Study (1997-2011) and Birth Defects Study to Evaluate Pregnancy exposureS (2014-2018).Pharmacoepidemiology and drug safety · 2023Article
- Toxicology knowledge graph for structural birth defects.Communications medicine · 2023Article
- Article
- Agreement between maternal report and medical records on use of medications during early pregnancy in New York.Birth defects research · 2023Article
- COVID-19 in pregnancy-what study designs can we use to assess the risk of congenital anomalies in relation to COVID-19 disease, treatment and vaccination?Paediatric and perinatal epidemiology · 2022Review
- Testing and Validating Semi-automated Approaches to the Occupational Exposure Assessment of Polycyclic Aromatic Hydrocarbons.Annals of work exposures and health · 2021Article
- The safety of asthma medications during pregnancy and lactation: Clinical management and research priorities.The Journal of allergy and clinical immunology · 2021Article
- Correlates of knowledge of genetic diseases and congenital anomalies among pregnant women attending antenatal clinics in Lagos, South-West Nigeria.The Pan African medical journal · 2021Article
- The Baby Hearts Study - a case-control methodology with data linkage to evaluate risk and protective factors for congenital heart disease.International journal of population data science · 2019Article
- The role of parental and perinatal characteristics on Langerhans cell histiocytosis: characterizing increased risk among Hispanics.Annals of epidemiology · 2018Article
- Editorial utility of population-based birth defects surveillance for monitoring the health of infants and as a foundation for etiologic research.Birth defects research. Part A, Clinical and molecular teratology · 2015Article
- Editorial perspectives from the founding CDC leadership of the National Birth Defects Prevention study.Birth defects research. Part A, Clinical and molecular teratology · 2015Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
backgroundThe Birth Defects Study To Evaluate Pregnancy exposureS (BD-STEPS) is a population-based, multi-Center case-control study of modifiable risk factors for selected birth defects in the United States. BD-STEPS is the second major research effort of the Centers for Birth Defects Research and Prevention, which extends and expands the initial research effort, the National Birth Defects Prevention Study (NBDPS).
methodsBD-STEPS focuses on 17 categories of structural birth defects selected based on severity, prevalence, consistent ascertainment, and previous findings that warrant additional research. Cases are identified through existing birth defects surveillance programs; controls are from vital records or birth hospital logs from the same catchment area. BD-STEPS uses a standardized computer-assisted telephone interview to collect information from case and control mothers on topics including demographics, health conditions, and medication use. Following the maternal interview, selected Centers request permission to sample residual newborn screening blood spots from state repositories for genetic analyses. New components planned for BD-STEPS include linkages with external datasets and use of online questionnaires to collect in-depth information on selected exposures.
resultsBD-STEPS extends NBDPS by continuing to collect data on many exposures that were assessed in NBDPS, allowing data from both studies to be combined and providing an unprecedented sample size to analyze rare exposures. BD-STEPS expands upon NBDPS by collecting more detailed information on existing exposures as well as new exposures.
conclusionThe goal of BD-STEPS is to provide women and healthcare providers with information they need to make decisions to promote the healthiest pregnancy possible.
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