ReviewCurrent opinion in virology2015
Influenza virus antigenicity and broadly neutralizing epitopes.
Review in Current opinion in virology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- Universal antibody targeting the highly conserved fusion peptide provides cross-protection in mice.Human vaccines & immunotherapeutics · 2022Article
- Article
- Antigenic characterization of influenza and SARS-CoV-2 viruses.Analytical and bioanalytical chemistry · 2022Review
- Core-Proteomics-Based Annotation of Antigenic Targets and Reverse-Vaccinology-Assisted Design of Ensemble Immunogen against the Emerging Nosocomial Infection-Causing BacteriumInternational journal of environmental research and public health · 2021Article
- Article
- Differential immune imprinting by influenza virus vaccination and infection in nonhuman primates.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Broad Reactivity Single Domain Antibodies against Influenza Virus and Their Applications to Vaccine Potency Testing and Immunotherapy.Biomolecules · 2021Review
- Construction, characterization, and immunization of nanoparticles that display a diverse array of influenza HA trimers.PloS one · 2021Article
- Serological Screening of Influenza A Virus Antibodies in Cats and Dogs Indicates Frequent Infection with Different Subtypes.Journal of clinical microbiology · 2020Article
- Targeting Hemagglutinin: Approaches for Broad Protection against the Influenza A Virus.Viruses · 2019Review
- Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses.Nature immunology · 2019Article
- Cross-lineage protection by human antibodies binding the influenza B hemagglutinin.Nature communications · 2019Article
- Influenza and Antibody-Dependent Cellular Cytotoxicity.Frontiers in immunology · 2019Review
- Structural Basis for the Broad, Antibody-Mediated Neutralization of H5N1 Influenza Virus.Journal of virology · 2018Article
- Recent advances in veterinary applications of structural vaccinology.Current opinion in virology · 2018Review
- Natural antibodies - facts known and unknown.Central-European journal of immunology · 2018Review
- Computational screening of known broad-spectrum antiviral small organic molecules for potential influenza HA stem inhibitors.PloS one · 2018Article
- Article
- High throughput discovery of influenza virus neutralizing antibodies from phage-displayed synthetic antibody libraries.Scientific reports · 2017Article
- A Special Connection between γδ T Cells and Natural Antibodies?Archivum immunologiae et therapiae experimentalis · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
A vaccine formulation that would be effective against all strains of influenza virus has long been a goal of vaccine developers, but antibodies after infection or vaccination were seen to be strain specific and there was little evidence of cross-reactive antibodies that neutralized across subtypes. Recently a number of broadly neutralizing monoclonal antibodies have been characterized. This review describes the different classes of broadly neutralizing antibodies and discusses the potential of their therapeutic use or for design of immunogens that induce a high proportion of broadly neutralizing antibodies.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.