ArticleBirth defects research. Part A, Clinical and molecular teratology2016
Residential radon and birth defects: A population-based assessment.
Article in Birth defects research. Part A, Clinical and molecular teratology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.
- Exposure to radon and ambient particle radioactivity during pregnancy and adverse maternal, fetal and perinatal outcomes: The current literature and potential mechanisms.Environmental research · 2024Pooled it
- Radon exposure and potential health effects other than lung cancer: a systematic review and meta-analysis.Frontiers in public health · 2024Pooled it
- Radon and Non-Cancer Pulmonary Health Effects in Children: A State of The Art Review.Pediatric pulmonology · 2026Review
- Article
- Associations Between Gestational Residential Radon Exposure and Term Low Birthweight in Connecticut, USA.Epidemiology (Cambridge, Mass.) · 2024Article
- A multidisciplinary and structured investigation of three suspected clusters of transverse upper limb reduction defects in France.European journal of epidemiology · 2024Article
- Examining the association between safe drinking water act violations and adverse birth outcomes in Virginia.Environmental research · 2023Article
- Associations between cumulative environmental quality and ten selected birth defects in Texas.Birth defects research · 2021Article
- Review
- Spatial Clusters of Children with Cleft Lip and Palate and Their Association with Polluted Zones in the Monterrey Metropolitan Area.International journal of environmental research and public health · 2019Article
- Residential Radon Exposure and Incidence of Childhood Lymphoma in Texas, 1995-2011.International journal of environmental research and public health · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundAssociations have been reported between maternal radiation exposure and birth defects. No such studies were found on radon. Our objective was to determine if there is an association between living in areas with higher radon levels and birth defects.
methodsThe Texas Birth Defects Registry provided data on all birth defects from 1999 to 2009 from the entire state. Mean radon levels by geologic region came from the Texas Indoor Radon Survey. The association between radon and birth defects was estimated using multilevel mixed effect Poisson regression.
resultsBirth defects overall were not associated with residential radon levels. Of the 100 other birth defect groups with at least 500 cases, 14 were significantly elevated in areas with high mean radon level in crude analyses, and 9 after adjustment for confounders. Cleft lip with/without cleft palate had an adjusted prevalence ratio of 1.16 per 1 picoCurie/liter (pCi/L) increase in exposure to region mean radon, 95% confidence interval, 1.08-1.26. Cystic hygroma / lymphangioma had an adjusted prevalence ratio of 1.22 per 1 pCi/L increase, 95% confidence interval, 1.02-1.46. Other associations were suggested but not as consistent: three skeletal defects, Down syndrome, other specified anomalies of the brain, and other specified anomalies of the bladder and urethra.
conclusionIn the first study of residential radon and birth defects, we found associations with cleft lip w/wo cleft palate and cystic hygroma / lymphangioma. Other associations were suggested. The ecological nature of this study and multiple comparisons suggest that our results be interpreted with caution.
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Registered trials
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