Evidence map›Paper›PMID 25846250›Full record

ReviewAdvanced healthcare materials2015

Biomaterials for Bone Regenerative Engineering.

Xiaohua Yu, Xiaoyan Tang, Shalini V Gohil, Cato T Laurencin

Abstract readReview
In one paragraph

Review in Advanced healthcare materials, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 144 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
144citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

144 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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84 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xiaohua YuInstitute for Regenerative Engineering, University of Connecticut Health Center, Farmington, CT, 06030, USA.
Xiaoyan TangInstitute for Regenerative Engineering, University of Connecticut Health Center, Farmington, CT, 06030, USA.
Shalini V GohilInstitute for Regenerative Engineering, University of Connecticut Health Center, Farmington, CT, 06030, USA.
Cato T LaurencinInstitute for Regenerative Engineering, University of Connecticut Health Center, Farmington, CT, 06030, USA.

Funding

A Translational Approach Towards Ligament RegenerationR01AR063698 · NIAMS · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI LAURENCIN, CATO T. · 2013 to 2018
$1.9M
NIAMS NIH HHS R01 AR063698
6 · The paper itself

Abstract

Strategies for bone tissue regeneration have been continuously evolving for the last 25 years since the introduction of the "tissue engineering" concept. The convergence of the life, physical, and engineering sciences has brought in several advanced technologies available to tissue engineers and scientists. This resulted in the creation of a new multidisciplinary field termed as "regenerative engineering". In this article, the role of biomaterials in bone regenerative engineering is systematically reviewed to elucidate the new design criteria for the next generation of biomaterials for bone regenerative engineering. The exemplary design of biomaterials harnessing various materials characteristics towards successful bone defect repair and regeneration is highlighted. Particular attention is given to the attempts of incorporating advanced materials science, stem cell technologies, and developmental biology into biomaterials design to engineer and develop the next generation bone grafts.

Indexed as

Bone RegenerationAnimalsBone SubstitutesHumansRegenerative MedicineTissue EngineeringBone Substitutesbiomaterialsbonecompositesosteogenesisregenerative engineering

Identifiers

PMID25846250
PMCPMC4507442

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.