Evidence map›Paper›PMID 25845626›Full record

ReviewCurrent opinion in neurobiology2015

How and why neural and motor variation are related.

Stephen G Lisberger, Javier F Medina

Abstract readReview
In one paragraph

Review in Current opinion in neurobiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Pharyngeal Pressure Variability During Volitional Swallowing Maneuvers.Journal of speech, language, and hearing research : JSLHR · 2022
    Article
  3. Atypical visual motion prediction abilities in autism spectrum disorder.Clinical psychological science : a journal of the Association for Psychological Science · 2021
    Article
  4. Perceptual-motor styles.Experimental brain research · 2021
    Review
  5. Article
  6. Article
  7. Increasing Muscle Speed Drives Changes in the Neuromuscular Transform of Motor Commands during Postnatal Development in Songbirds.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020
    Article
  8. Sensorimotor Coding of Vermal Granule Neurons in the Developing Mammalian Cerebellum.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019
    Article
  9. Fluctuations in Human Corticospinal Activity Prior to Grasp.Frontiers in systems neuroscience · 2019
    Article
  10. Article
  11. Individual Movement Variability Magnitudes Are Explained by Cortical Neural Variability.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017
    Article
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Stephen G LisbergerDepartment of Neurobiology, Howard Hughes Medical Institute, Duke University School of Medicine, Durham, NC, United States. Electronic address: lisberger@neuro.duke.edu.
Javier F MedinaDepartment of Psychology, University of Pennsylvania, Philadelphia, PA, United States.

Funding

Variation as a Neural CodeP50MH077970 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BRAINARD, MICHAEL S · 2006 to 2010
$9.6M
Coding and processing of error signals in inferior olivary-cerebellar networksR01MH093727 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI JAVIER F MEDINA · 2011 to 2026
$6.7M
NEURAL CONTROL OF EYE MOVEMENTR01EY003878 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LISBERGER, STEPHEN G · 1985 to 2013
$2.5M
Collaborative research: CRCNS: Precision and coding in smooth pursuitR01EY017210 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LISBERGER, STEPHEN G · 2005 to 2010
$1.7M
NEURAL CONTROL OF EYE MOVEMENTR37EY003878 · NEI · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · PI LISBERGER, STEPHEN G · 1989 to 1998
–
Howard Hughes Medical InstituteNEI NIH HHS EY017210NEI NIH HHS EY03878NEI NIH HHS R01 EY003878NEI NIH HHS R01 EY017210NIMH NIH HHS P50 MH077970NIMH NIH HHS R01 MH093727
6 · The paper itself

Abstract

Movements are variable. Recent findings in smooth pursuit eye movements provide an explanation for motor variation in terms of the organization of the brain's sensory-motor pathways. Variation in sensory estimation is propagated through sensory-motor circuits and ultimately causes motor variation. The sensory origin of motor variation creates trial-by-trial correlations among the responses of neurons at each level of the sensory motor circuit, and between neural and behavioral responses. We suggest that motor variation is a compromise between multiple competing constraints. The brain strives for motor behavior that is 'good enough' in the face of constraints that tend to promote variation.

Indexed as

Models, NeurologicalAction PotentialsAnimalsHumansMotion PerceptionMovementNeuronsPursuit, Smooth

Identifiers

PMID25845626
PMCPMC4576830

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.