ArticlePloS one2015
Necrotrophic effector epistasis in the Pyrenophora tritici-repentis-wheat interaction.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 41 citations in OpenAlex.
- Genome-wide association mapping of tan spot resistance in a modified NAM population derived from synthetic hexaploid wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Identification of resistance sources and genomic regions regulating spot blotch resistance in Asian bread wheat (Triticum aestivum L.) via genome-wide association study.The plant genome · 2026Article
- A new family of structurally conserved fungal effectors displays epistatic interactions with plant resistance proteins.PLoS pathogens · 2022Article
- Variability in an effector gene promoter of a necrotrophic fungal pathogen dictates epistasis and effector-triggered susceptibility in wheat.PLoS pathogens · 2022Article
- An optimized sporulation method for the wheat fungal pathogen Pyrenophora tritici-repentis.Plant methods · 2021Article
- Effectors of Plant Necrotrophic Fungi.Frontiers in plant science · 2021Review
- Genome-wide association mapping of tan spot resistance in a worldwide collection of durum wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2020Article
- Genetics of Variable Disease Expression Conferred by Inverse Gene-For-Gene Interactions in the Wheat-Plant physiology · 2019Article
- Characterizing Virulence of thePathogens (Basel, Switzerland) · 2018Article
- Comparative genomics of the wheat fungal pathogen Pyrenophora tritici-repentis reveals chromosomal variations and genome plasticity.BMC genomics · 2018Article
- Inverse gene-for-gene interactions contribute additively to tan spot susceptibility in wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2017Article
- Regulation of proteinaceous effector expression in phytopathogenic fungi.PLoS pathogens · 2017Review
- A functionally conserved ZnMolecular plant pathology · 2017Article
- New Insights into the Roles of Host Gene-Necrotrophic Effector Interactions in Governing Susceptibility of Durum Wheat to Tan Spot and Septoria nodorum Blotch.G3 (Bethesda, Md.) · 2016Article
- Differential effector gene expression underpins epistasis in a plant fungal disease.The Plant journal : for cell and molecular biology · 2016Article
- Genetic relationships between race-nonspecific and race-specific interactions in the wheat-Pyrenophora tritici-repentis pathosystem.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2016Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pyrenophora tritici-repentis, the causal agent of tan spot disease of wheat, mediates disease by the production of host-selective toxins (HST). The known toxins are recognized in an 'inverse' gene-for-gene manner, where each is perceived by the product of a unique locus in the host and recognition leads to disease susceptibility. Given the importance of HSTs in disease development, we would predict that the loss of any of these major pathogenicity factors would result in reduced virulence and disease development. However, after either deletion of the gene encoding the HST ToxA or, reciprocally, heterologous expression of ToxA in a race that does not normally produce the toxin followed by inoculation of ToxA-sensitive and insensitive wheat cultivars, we demonstrate that ToxA symptom development can be epistatic to other HST-induced symptoms. ToxA epistasis on certain ToxA-sensitive wheat cultivars leads to genotype-specific increases in total leaf area affected by disease. These data indicate a complex interplay between host responses to HSTs in some genotypes and underscore the challenge of identifying additional HSTs whose activity may be masked by other toxins. Also, through mycelial staining, we acquire preliminary evidence that ToxA may provide additional benefits to fungal growth in planta in the absence of its cognate recognition partner in the host.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.