Evidence map›Paper›PMID 25844857›Full record

Trial reportJournal of athletic training2015

Short-Wave Diathermy Pretreatment and Inflammatory Myokine Response After High-Intensity Eccentric Exercise.

John P Vardiman, Nicole Moodie, Jacob A Siedlik, Rebecca A Kudrna, Zachary Graham, Philip Gallagher

Open access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of athletic training, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

John P VardimanApplied Physiology Laboratory, University of Kansas, Lawrence;
Nicole MoodieExercise and Sport Science Department, Rockhurst University, Kansas City, MO;
Jacob A SiedlikApplied Physiology Laboratory, University of Kansas, Lawrence;
Rebecca A KudrnaDesales University, Center Valley, PA.
Zachary GrahamApplied Physiology Laboratory, University of Kansas, Lawrence;
Philip GallagherApplied Physiology Laboratory, University of Kansas, Lawrence;
University of Kansas · USDeSales University · USRockhurst University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextVarious modalities have been used to pretreat skeletal muscle to attenuate inflammation.

objectiveTo determine the effects of short-wave diathermy (SWD) preheating treatment on inflammation and stress markers after eccentric exercise.

designControlled laboratory study.

settingUniversity laboratory setting. PATIENTS OR OTHER

participantsFifteen male (age = 22 ± 4.9 years, height = 179.75 ± 9.56 cm, mass = 82.22 ± 12.67 kg) college-aged students. INTERVENTION(S): Seven participants were selected randomly to receive 40 minutes of SWD heat treatment (HT), and 8 participants served as the control (CON) group and rested without SWD. Both groups completed 7 sets of 10 repetitions of a high-intensity eccentric exercise protocol (EEP) at 120% of the 1-repetition maximum (1-RM) leg extension. MAIN OUTCOME MEASURE(S): We biopsied muscles on days 1, 3 (24 hours post-EEP), and 4 (48 hours post-EEP) and collected blood samples on days 1, 2 (4 hours post-EEP), 3, and 4. We determined 1-RM on day 2 (24 hours post-SWD) and measured 1-RM on days 3 and 4. We analyzed the muscle samples for interleukin 6 (IL-6), tumor necrosis factor α, and heat shock protein 70 and the blood for serum creatine kinase.

resultsWe found a group × time interaction for intramuscular IL-6 levels after SWD (F2,26 = 7.13, P = .003). The IL-6 decreased in HT (F1,6 = 17.8, P = .006), whereas CON showed no change (P > .05). We found a group × time interaction for tumor necrosis factor α levels (F2,26 = 3.71, P = .04), which increased in CON (F2,14 = 7.16, P = .007), but saw no changes for HT (P > .05). No group × time interactions were noted for 1-RM, heat shock protein 70, or creatine kinase (P > .05).

conclusionsThe SWD preheating treatment provided a treatment effect for intramuscular inflammatory myokines induced through high-intensity eccentric exercise but did not affect other factors associated with intense exercise and inflammation.

Indexed as

BiomarkersCreatine KinaseCytokinesDiathermyExerciseHSP70 Heat-Shock ProteinsHumansInterleukin-6MaleMuscle, SkeletalMyositisTumor Necrosis Factor-alphaYoung AdultBiomarkersCreatine KinaseCytokinesHSP70 Heat-Shock ProteinsIL6 protein, humanInterleukin-6TNF protein, humanTumor Necrosis Factor-alphacytokinesinflammationinterleukin-6tumor necrosis factor α

Identifiers

PMID25844857
PMCPMC4527445
OpenAlexW2052714951

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.