Evidence map›Paper›PMID 25844644›Full record

ArticlePloS one2015

Restoring susceptibility induced MRI signal loss in rat brain at 9.4 T: A step towards whole brain functional connectivity imaging.

Rupeng Li, Xiping Liu, Jason W Sidabras, Eric S Paulson, Andrzej Jesmanowicz, Andrew S Nencka, Anthony G Hudetz, James S Hyde

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
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  12. Autobiography of James S. Hyde.Applied magnetic resonance · 2017
    Article
  13. Article
  14. Review
  15. MRI surface-coil pair with strong inductive coupling.The Review of scientific instruments · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Rupeng LiDepartment of Biophysics, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America.
Xiping LiuDepartment of Dermatology, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America.
Jason W SidabrasDepartment of Biophysics, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America.
Eric S PaulsonDepartment of Radiation Oncology, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America.
Andrzej JesmanowiczDepartment of Biophysics, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America.
Andrew S NenckaDepartment of Biophysics, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America.
Anthony G HudetzDepartment of Anesthesiology, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America.
James S HydeDepartment of Biophysics, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America.
Medical College of Wisconsin · US

Funding

LOOP GAP RESONATOR COILS FOR MRI AND 31P SPECTROSCOPYR01EB000215 · NIBIB · MEDICAL COLLEGE OF WISCONSIN · PI JESMANOWICZ, ANDRZEJ · 2002 to 2014
$5.8M
NIBIB NIH HHS R01 EB000215
6 · The paper itself

Abstract

The aural cavity magnetic susceptibility artifact leads to significant echo planar imaging (EPI) signal dropout in rat deep brain that limits acquisition of functional connectivity fcMRI data. In this study, we provide a method that recovers much of the EPI signal in deep brain. Needle puncture introduction of a liquid-phase fluorocarbon into the middle ear allows acquisition of rat fcMRI data without signal dropout. We demonstrate that with seeds chosen from previously unavailable areas, including the amygdala and the insular cortex, we are able to acquire large scale networks, including the limbic system. This tool allows EPI-based neuroscience and pharmaceutical research in rat brain using fcMRI that was previously not feasible.

Indexed as

AnimalsBrainBrain MappingEar, MiddleEcho-Planar ImagingFluorocarbonsImage Processing, Computer-AssistedRadiographyRatsFluorocarbons

Identifiers

PMID25844644
PMCPMC4386820
OpenAlexW2036348121

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.