Evidence map›Paper›PMID 25844400›Full record

ArticleJournal of syndromes2013

IPEX Syndrome, FOXP3 and Cancer.

Runhua Liu, Silin Li, Wei-Hsiung Yang, Lizhong Wang

Open access · diamondAbstract read
In one paragraph

Article in Journal of syndromes, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact, top 67% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. FOXP3 expression is modulated by TGF‑β1/NOTCH1 pathway in human melanoma.International journal of molecular medicine · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Runhua LiuDepartment of Genetics, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA.
Silin LiComprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA.
Wei-Hsiung YangDepartment of Biomedical Sciences, Mercer University School of Medicine, Savannah, Georgia 31404, USA.
Lizhong Wang
University of Alabama at Birmingham · US

Funding

FOXP3-microRNA146-NFkB Axis in Tumor SuppressionR21CA164688 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI WANG, LIZHONG · 2012 to 2013
$341k
NCI NIH HHS R21 CA164688
6 · The paper itself

Abstract

In this review, we introduce the IPEX syndrome and its relationship with germline mutations of the FOXP3 gene. We then describe the multiple functional roles of FOXP3 in regulatory T cells and epithelial cells as well as in IPEX syndrome and tumor progression. Potential mechanisms of

Indexed as

CancerFOXP3IPEXSyndromeTumor suppressors

Identifiers

PMID25844400
PMCPMC4383293
OpenAlexW2411988794

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.