Evidence map›Paper›PMID 25844398›Full record

ArticleeNeuro

FMRP regulates neurogenesis

Regina L Faulkner, Tyler J Wishard, Christopher K Thompson, Han-Hsuan Liu, Hollis T Cline

Open access · goldAbstract read
In one paragraph

Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Assessing circuit function in the developingFrontiers in behavioral neuroscience · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Experience-Dependent Development of Dendritic Arbors in Mouse Visual Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020
    Article
  9. [Progress on neurogenesis mechanisms of endogenous adult neural stem cells].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2018
    Review
  10. Neural architecture: from cells to circuits.Journal of neurophysiology · 2018
    Review
  11. Review
  12. Modeling Fragile X Syndrome inFrontiers in molecular neuroscience · 2018
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Regina L FaulknerThe Dorris Neuroscience Center, Department of Molecular and Cellular Neuroscience, The Scripps Research Institute, La Jolla, California 92037.
Tyler J WishardUniversity of California, San Diego, La Jolla, California 92037.
Christopher K ThompsonThe Dorris Neuroscience Center, Department of Molecular and Cellular Neuroscience, The Scripps Research Institute, La Jolla, California 92037.
Han-Hsuan LiuThe Dorris Neuroscience Center, Department of Molecular and Cellular Neuroscience, The Scripps Research Institute, La Jolla, California 92037 ; Kellogg School of Science and Technology, The Scripps Research Institute, La Jolla, California 92037.
Hollis T ClineThe Dorris Neuroscience Center, Department of Molecular and Cellular Neuroscience, The Scripps Research Institute, La Jolla, California 92037.
Scripps Research Institute · USUniversity of California System · US

Funding

Activity-dependent Development of Visual System DevelopmentR01EY011261 · NEI · SCRIPPS RESEARCH INSTITUTE, THE · PI CLINE, HOLLIS T. · 1996 to 2018
$11.1M
UCSD MARC ProgramT34GM087193 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ARTIS, DAVID, CHIEN, SHU · 2009 to 2014
$2.3M
Effects of environmental thyroid hormone disrupting compounds on CNS developmentR00ES022992 · NIEHS · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI THOMPSON, CHRISTOPHER KIRK · 2017 to 2019
$612k
Effects of environmental thyroid hormone disrupting compounds on CNS developmentK99ES022992 · NIEHS · SCRIPPS RESEARCH INSTITUTE, THE · PI THOMPSON, CHRISTOPHER KIRK · 2013 to 2014
$178k
Experience-dependent development of neural circuits in the Xenopus visual systemF32NS071807 · NINDS · SCRIPPS RESEARCH INSTITUTE, THE · PI FAULKNER, REGINA L · 2011 to 2013
$155k
NEI NIH HHS R01 EY011261NIEHS NIH HHS K99 ES022992NIEHS NIH HHS R00 ES022992NIGMS NIH HHS T34 GM087193NINDS NIH HHS F32 NS071807
6 · The paper itself

Abstract

Fragile X Syndrome (FXS) is the leading known monogenic form of autism and the most common form of inherited intellectual disability. FXS results from silencing the

Indexed as

Fragile X Messenger Ribonucleoprotein 1NeurogenesisNeuronsAnimalsAnimals, Genetically ModifiedApoptosisCell DifferentiationCell ProliferationGene Expression Regulation, DevelopmentalLarvaNeural Stem CellsNeurodevelopmentSuperior ColliculiTime-Lapse ImagingXenopus laevisFragile X Messenger Ribonucleoprotein 1

Identifiers

PMID25844398
PMCPMC4384423
OpenAlexW1981540260

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.