Evidence map›Paper›PMID 25844087›Full record

ArticleFrontiers in biology2014

Comparative analysis of chromosome segregation in human, yeasts and trypanosome.

Xianxian Han, Ziyin Li

Abstract read
In one paragraph

Article in Frontiers in biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Xianxian HanDepartment of Microbiology and Molecular Genetics, University of Texas Medical School, Houston, TX 77030, USA.
Ziyin LiDepartment of Microbiology and Molecular Genetics, University of Texas Medical School, Houston, TX 77030, USA.

Funding

Mechanisms Of The Unusual Cytokinesis In TrypanosomesR01AI101437 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI LI, ZIYIN · 2013 to 2025
$6.4M
Mechanisms of mitochondrial DNA replication licensing in trypanosomesR21AI093897 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI LI, ZIYIN · 2012 to 2013
$418k
NIAID NIH HHS R01 AI101437NIAID NIH HHS R21 AI093897
6 · The paper itself

Abstract

Chromosome segregation is a tightly regulated process through which duplicated genetic materials are equally partitioned into daughter cells. During the past decades, tremendous efforts have been made to understand the molecular mechanism of chromosome segregation using animals and yeasts as model systems. Recently, new insights into chromosome segregation have gradually emerged using trypanosome, an early branching parasitic protozoan, as a model organism. To uncover the unique aspects of chromosome segregation in trypanosome, which potentially could serve as new drug targets for anti-trypanosome chemotherapy, it is necessary to perform a comparative analysis of the chromosome segregation machinery between trypanosome and its human host. Here, we briefly review the current knowledge about chromosome segregation in human and

Indexed as

anaphase promoting complexcohesinsecurinseparasespindle assembly checkpointTrypanosoma brucei

Identifiers

PMID25844087
PMCPMC4384469
OpenAlexW2016413776

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.