Evidence map›Paper›PMID 25843609›Full record

ReviewMethods (San Diego, Calif.)2015

Infected animal models for tissue engineering.

Alexander M Tatara, Sarita R Shah, Carissa E Livingston, Antonios G Mikos

Abstract readReview
In one paragraph

Review in Methods (San Diego, Calif.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
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  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alexander M TataraDepartment of Bioengineering, Rice University, Houston, TX 77030, United States.
Sarita R ShahDepartment of Bioengineering, Rice University, Houston, TX 77030, United States.
Carissa E LivingstonDepartment of Bioengineering, Rice University, Houston, TX 77030, United States.
Antonios G MikosDepartment of Bioengineering, Rice University, Houston, TX 77030, United States; Department of Chemical and Biomolecular Engineering, Rice University, Houston, TX 77005, United States. Electronic address: mikos@rice.edu.

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007330 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI PLON, SHARON E. · 1985 to 2019
$15.6M
NIGMS NIH HHS T32 GM007330
6 · The paper itself

Abstract

Infection is one of the most common complications associated with medical interventions and implants. As tissue engineering strategies to replace missing or damaged tissue advance, the focus on prevention and treatment of concomitant infection has also begun to emerge as an important area of research. Because the in vivo environment is a complex interaction between host tissue, implanted materials, and native immune system that cannot be replicated in vitro, animal models of infection are integral in evaluating the safety and efficacy of experimental treatments for infection. In this review, considerations for selecting an animal model, established models of infection, and areas that require further model development are discussed with regard to cutaneous, fascial, and orthopedic infections.

Indexed as

AnimalsConnective Tissue DiseasesDisease Models, AnimalHerniorrhaphyHost SpecificityHumansInfectionsOsteomyelitisSkin Diseases, InfectiousTissue EngineeringAnimal modelInfectionIn vivoPreclinicalTissue engineering

Identifiers

PMID25843609
PMCPMC4526327

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.