Evidence map›Paper›PMID 25843390›Full record

ArticleEpidemics2015

Four key challenges in infectious disease modelling using data from multiple sources.

Daniela De Angelis, Anne M Presanis, Paul J Birrell, Gianpaolo Scalia Tomba, Thomas House

Abstract read
In one paragraph

Article in Epidemics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Key questions for modelling COVID-19 exit strategies.Proceedings. Biological sciences · 2020
    Pooled it
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  7. A PARTIALLY DIFFUSIVE MODEL FOR FROGEYE LEAF SPOT EPIDEMICS IN SOYBEAN.Discrete and continuous dynamical systems. Series B · 2026
    Article
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  11. Article
  12. Review
  13. Estimating epidemic dynamics with genomic and time series data.Journal of the Royal Society, Interface · 2025
    Article
  14. Article
  15. Research gaps and priorities for quantitative microbial risk assessment (QMRA).Risk analysis : an official publication of the Society for Risk Analysis · 2024
    Article
  16. Review
  17. Accurate Estimation of Individual Transmission Rates Through Contact Analytics Using UWB Based Indoor Location Data.International Conference on Smart Applications, Communications and Networking : SmartNets. International Conference on Smart Applications, Communications and Networking · 2024
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Daniela De AngelisMRC Biostatistics Unit, Cambridge Institute of Public Health, Robinson Way, Cambridge CB2 0SR, UK; Public Health England, 61 Colindale Avenue, London NW9 5HT, UK. Electronic address: daniela.deangelis@mrc-bsu.cam.ac.uk.
Anne M PresanisMRC Biostatistics Unit, Cambridge Institute of Public Health, Robinson Way, Cambridge CB2 0SR, UK.
Paul J BirrellMRC Biostatistics Unit, Cambridge Institute of Public Health, Robinson Way, Cambridge CB2 0SR, UK.
Gianpaolo Scalia TombaDepartment of Mathematics, University of Rome Tor Vergata, Rome, Italy.
Thomas HouseWarwick Mathematics Institute, University of Warwick, Coventry CV4 7AL, UK.

Funding

Department of Health 11/46/03Medical Research Council MC_U105260556Medical Research Council U105260566
6 · The paper itself

Abstract

Public health-related decision-making on policies aimed at controlling epidemics is increasingly evidence-based, exploiting multiple sources of data. Policy makers rely on complex models that are required to be robust, realistically approximating epidemics and consistent with all relevant data. Meeting these requirements in a statistically rigorous and defendable manner poses a number of challenging problems. How to weight evidence from different datasets and handle dependence between them, efficiently estimate and critically assess complex models are key challenges that we expound in this paper, using examples from influenza modelling.

Indexed as

Communicable DiseasesData CollectionEpidemicsHumansModels, StatisticalStatistics as TopicBayesianComplex modelsEpidemicsEvidence synthesisMultiple sourcesStatistical inference

Identifiers

PMID25843390
PMCPMC4383805

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.