Evidence map›Paper›PMID 25843334›Full record

ArticleBiological psychiatry2015

Genotype-first analysis of the 16p11.2 deletion defines a new type of "autism".

Michael H Duyzend, Evan E Eichler

Abstract readComment
In one paragraph

Article in Biological psychiatry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Characterizing Sleep Problems in 16p11.2 Deletion and Duplication.Journal of autism and developmental disorders · 2023
    Article
  3. Review
  4. Quantitative gait assessment in children with 16p11.2 syndrome.Journal of neurodevelopmental disorders · 2019
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. COPD diagnosis: genome first.Journal of thoracic disease · 2015
    Article
  10. Translational genetic research of complex diseases.Journal of translational internal medicine
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Michael H DuyzendDepartment of Genome Sciences, University of Washington School of Medicine, Seattle, Washington.
Evan E EichlerDepartment of Genome Sciences, University of Washington School of Medicine, Seattle, Washington; Howard Hughes Medical Institute, University of Washington School of Medicine, Seattle, Washington. Electronic address: eee@gs.washington.edu.

Funding

University of Washington Medical Scientist Training Program: MD/PhDT32GM007266 · NIGMS · UNIVERSITY OF WASHINGTON · PI HORWITZ, MARSHALL S. · 1985 to 2023
$30.4M
Sporadic Mutations and Autism Spectrum DisordersR01MH101221 · NIMH · UNIVERSITY OF WASHINGTON · PI EICHLER, EVAN · 2013 to 2025
$9.2M
Intellectual and Developmental Disabilities Research CenterU54HD083091 · NICHD · UNIVERSITY OF WASHINGTON · PI GURALNICK, MICHAEL J · 2014 to 2019
$7.9M
The genetic basis underlying the phenotype heterogeneity of the 16p11.2 CNVF30MH105055 · NIMH · UNIVERSITY OF WASHINGTON · PI DUYZEND, MICHAEL H · 2014 to 2017
$177k
Howard Hughes Medical InstituteNICHD NIH HHS U54 HD083091NIGMS NIH HHS T32 GM007266NIMH NIH HHS 1F30MH105055-01NIMH NIH HHS F30 MH105055NIMH NIH HHS R01 MH101221NIMH NIH HHS R01MH101221
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Chromosome DeletionChromosomes, Human, Pair 16CognitionPhenotypeDevelopmental DisabilitiesHumansMental Disorders

Identifiers

PMID25843334
PMCPMC4657856

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.