Evidence map›Paper›PMID 25843260›Full record

ArticleJournal of biomechanics2015

The impact of boundary conditions on surface curvature of polypropylene mesh in response to uniaxial loading.

William R Barone, Rouzbeh Amini, Spandan Maiti, Pamela A Moalli, Steven D Abramowitch

Abstract read
In one paragraph

Article in Journal of biomechanics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. International guidelines for groin hernia management.Hernia : the journal of hernias and abdominal wall surgery · 2018
    Guideline
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Exploring the basic science of prolapse meshes.Current opinion in obstetrics & gynecology · 2016
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

William R BaroneMusculoskeletal Research Center, Department of Bioengineering, University of Pittsburgh, 405 Center for Bioengineering, 300 Technology Drive, Pittsburgh, PA 15219, USA. Electronic address: wbb8@pitt.edu.
Rouzbeh AminiDepartment of Bioengineering, University of Pittsburgh, Department of Biomedical Engineering, The University of Akron, 260 S. Forge St., Akron, OH 44325, USA. Electronic address: ramini@uakron.edu.
Spandan MaitiDepartment of Bioengineering, University of Pittsburgh, 360B Center for Bioengineering, 300 Technology Drive, Pittsburgh, PA 15219, USA. Electronic address: spm54@pitt.edu.
Pamela A MoalliMagee-Womens Research Institute, Magee-Womens Hospital, University of Pittsburgh, 204 Craft Avenue, Pittsburgh, PA 15213, USA. Electronic address: moalpa@mail.magee.edu.
Steven D AbramowitchMagee-Womens Research Institute, Magee-Womens Hospital, University of Pittsburgh, Musculoskeletal Research Center, Department of Bioengineering, University of Pittsburgh, 405 Center for Bioengineering, 300 Technology Drive, Pittsburgh, PA 15219, USA. Electronic address: sdast9@pitt.edu.

Funding

Building Research Careers in Women's HealthK12HD043441 · NICHD · MAGEE-WOMEN'S RES INST AND FOUNDATION · PI SADOVSKY, YOEL · 2002 to 2023
$10.1M
Porosity and tensioning: Critical factors to consider when choosing a prolapse meshR01HD083383 · NICHD · MAGEE-WOMEN'S RES INST AND FOUNDATION · PI ABRAMOWITCH, STEVEN D, MOALLI, PAMELA A. · 2016 to 2025
$5.5M
Comprehensive Evaluation of Prolapse Meshes by an Interdisciplinary Research TeamR01HD061811 · NICHD · MAGEE-WOMEN'S RES INST AND FOUNDATION · PI MOALLI, PAMELA A. · 2009 to 2013
$2.1M
IMPACT OF MENOPAUSE ON VAGINAL CONNECTIVE TISSUE SUPPORTR01HD045590 · NICHD · MAGEE-WOMEN'S RES INST AND FOUNDATION · PI MOALLI, PAMELA A. · 2004 to 2008
$1.4M
NICHD NIH HHS K12 HD043441NICHD NIH HHS K12HD-043441NICHD NIH HHS R01 HD045590NICHD NIH HHS R01HD-045590NICHD NIH HHS R01 HD061811NICHD NIH HHS R01 HD083383
6 · The paper itself

Abstract

Exposure following pelvic organ prolapse repair has been observationally associated with wrinkling of the implanted mesh. The purpose of this study was to quantify the impact of variable boundary conditions on the out-of-plane deformations of mesh subjected to tensile loading. Using photogrammetry and surface curvature analyses, deformed geometries were accessed for two commercially available products. Relative to standard clamping methods, the amount of out-of-plane deformation significantly increased when point loads were introduced to simulate suture fixation in-vivo. These data support the hypothesis that regional increases in the concentration of mesh potentially enhance the host׳s foreign body response, leading to exposure.

Indexed as

Prostheses and ImplantsSurgical MeshComputer SimulationEquipment Failure AnalysisFemaleHumansMaterials TestingPelvic Organ ProlapsePolypropylenesSuturesTensile StrengthPolypropylenesBoundary conditionsExposureMeshPelvic organ prolapsePhotogrammetrySurface curvature

Identifiers

PMID25843260
PMCPMC4550315

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.