Evidence map›Paper›PMID 25841984›Full record

ArticleDrug and alcohol dependence2015

Prevalence and experience of chronic pain in suburban drug injectors.

Robert Heimer, Weihai Zhan, Lauretta E Grau

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Drug and alcohol dependence, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06581276 (Increasing Access to Evidence-based Treatment for Chronic Pain and Opioid Use Disorder), which is not on this map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06581276 nacompletednot on this mapstarted 2023, after this paper: background citation

Increasing Access to Evidence-based Treatment for Chronic Pain and Opioid Use Disorder: Adapting Acceptance and Commitment Therapy for Opioid Treatment Programs

TypeinterventionalSponsorMontefiore Medical CenterRan2023 to 2024Enrolled7ConditionsOpioid Use, Opioid Use Disorder, Chronic PainArmsAcceptance and Commitment Therapy (ACT)
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
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  10. Prevalent Misconceptions About Opioid Use Disorders in the United States Produce Failed Policy and Public Health Responses.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2019
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  12. Review
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  16. Mu Opioid Receptor Modulation of Dopamine Neurons in the Periaqueductal Gray/Dorsal Raphe: A Role in Regulation of Pain.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2016
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Robert HeimerCenter for Interdisciplinary Research on AIDS and the Department of Epidemiology of Microbial Disease, Yale University School of Public Health, 60 College Street, New Haven, CT 06520, United States. Electronic address: robert.heimer@yale.edu.
Weihai ZhanCenter for Interdisciplinary Research on AIDS and the Department of Epidemiology of Microbial Disease, Yale University School of Public Health, 60 College Street, New Haven, CT 06520, United States.
Lauretta E GrauCenter for Interdisciplinary Research on AIDS and the Department of Epidemiology of Microbial Disease, Yale University School of Public Health, 60 College Street, New Haven, CT 06520, United States.
Yale University · US

Funding

Parenteral HCV Transmission: Assessing Risks and Prevention Strategies in vitroR01DA030420 · NIDA · YALE UNIVERSITY · PI ABDALA, NADIA · 2011 to 2015
$2.3M
NIDA NIH HHS R01 DA030420
6 · The paper itself

Abstract

aimsTo explore the relationship between chronic pain and characteristics, behaviors, and psychological status of suburban Connecticut injection drug users.

methodsCross-sectional study with quantitative interview and serological testing for HIV and hepatitis B and C in 456 individuals who injected drugs in the past month. Participants were dichotomized into those reporting current chronic pain of at least six months duration and all others. The interview covered (i) sociodemographics, (ii) injection drug use, (iii) interactions with drug treatment, criminal justice, and harm reduction, (iv) screening for alcohol use, chronic pain, anxiety, and depression, and (v) knowledge regarding HIV, hepatitis B (HBV) and C (HCV), and opioid overdose. Serological testing for HIV, HBV, and HCV was conducted.

resultsOne-third (n = 143) reported chronic pain. These individuals differed significantly from those not reporting chronic pain on characteristics that included older age, lower educational achievement, and injection of pharmaceutical opioids. They also reported experiencing more psychological and family problems on the ASI and higher levels of depression and anxiety. Four of five individuals with chronic pain (n = 117) reported non-medical opioid use prior to the onset of chronic pain.

conclusionsChronic pain is common among drug injectors in our study population although it was unusual for chronic pain to have preceded non-medical opioid use. Psychological problems in injectors with co-occurring chronic pain are likely pose significant complications to successful treatment for substance abuse, pain, or infectious disease treatment.

Indexed as

Pain PerceptionAdultAge FactorsAnalgesics, OpioidChronic PainConnecticutCross-Sectional StudiesEducational StatusFemaleHumansInterviews as TopicMaleMiddle AgedNarcoticsOpioid-Related DisordersPrevalenceAnalgesics, OpioidNarcoticsAnxietyChronic painDepressionInjection drug useOpioidsSuburbs

Identifiers

PMID25841984
PMCPMC4447527
OpenAlexW2035405008

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.