Evidence map›Paper›PMID 25841800›Full record

ArticleMicrobes and infection2015

Filifactor alocis--a new emerging periodontal pathogen.

A Wilson Aruni, Arunima Mishra, Yuetan Dou, Ozioma Chioma, Brittany N Hamilton, Hansel M Fletcher

Open access · greenAbstract read
In one paragraph

Article in Microbes and infection, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed, 1 pooled it
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 1 synthesis or guideline pooled it, 120 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Observational
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Quantitative real-time PCR detection ofJournal of medical microbiology · 2025
    Article
  14. Article
  15. Article
  16. Adjunctive use of3 Biotech · 2025
    Article
  17. Increased bacterial load ofFrontiers in oral health · 2025
    Article
  18. Article
  19. Association ofDentistry journal · 2024
    Article
  20. Review

13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

A Wilson AruniDivision of Microbiology and Molecular Genetics, School of Medicine, Loma Linda University, CA 92354, USA.
Arunima MishraDivision of Microbiology and Molecular Genetics, School of Medicine, Loma Linda University, CA 92354, USA.
Yuetan DouDivision of Microbiology and Molecular Genetics, School of Medicine, Loma Linda University, CA 92354, USA.
Ozioma ChiomaDivision of Microbiology and Molecular Genetics, School of Medicine, Loma Linda University, CA 92354, USA.
Brittany N HamiltonDivision of Microbiology and Molecular Genetics, School of Medicine, Loma Linda University, CA 92354, USA.
Hansel M FletcherDivision of Microbiology and Molecular Genetics, School of Medicine, Loma Linda University, CA 92354, USA; Institute of Oral Biology, Kyung Hee University, Seoul, Republic of Korea. Electronic address: hfletcher@llu.edu.
Loma Linda University · US

Funding

NIH-LLU Initiative for Maximizing Student DiversityR25GM060507 · NIGMS · LOMA LINDA UNIVERSITY · PI DE LEON, MARINO · 2001 to 2022
$11.3M
Research Training/Education CoreP20MD006988 · NIMHD · LOMA LINDA UNIVERSITY · PI CASIANO, CARLOS A. · 2012 to 2016
$6.2M
Studies on virulence regulation in PorphyromonasR01DE013664 · NIDCR · LOMA LINDA UNIVERSITY · PI FLETCHER, HANSEL M. · 2002 to 2011
$3.3M
Mechanisms for adaptation to oxidative stress in Porphyromonas gingivalisR01DE019730 · NIDCR · LOMA LINDA UNIVERSITY · PI FLETCHER, HANSEL M. · 2009 to 2013
$2.0M
ECF sigma factors in adaptation and virulence of Porphyromonas gingivalisR01DE022508 · NIDCR · LOMA LINDA UNIVERSITY · PI FLETCHER, HANSEL M. · 2012 to 2016
$1.8M
Studies on the virulence of Fillifactor alocisR21DE022724 · NIDCR · LOMA LINDA UNIVERSITY · PI FLETCHER, HANSEL M. · 2012 to 2013
$427k
Studies on the virulence regulation in PorphyromonasR56DE013664 · NIDCR · LOMA LINDA UNIVERSITY · PI FLETCHER, HANSEL M. · 2014 to 2014
$291k
NIDCR NIH HHS DE019730NIDCR NIH HHS DE019730 04S1NIDCR NIH HHS DE022508NIDCR NIH HHS DE022724NIDCR NIH HHS R01 DE013664NIDCR NIH HHS R01 DE019730NIDCR NIH HHS R01 DE022508NIDCR NIH HHS R21 DE022724NIDCR NIH HHS R56 DE013664NIDCR NIH HHS R-56-DE13664NIGMS NIH HHS R25 GM060507NIMHD NIH HHS P20 MD006988
6 · The paper itself

Abstract

Filifactor alocis, a previously unrecognized Gram-positive anaerobic rod, is now considered a new emerging pathogen that may play a significant role in periodontal disease. F. alocis' unique characteristics and variations at the molecular level that may be responsible for the functional changes required to mediate the pathogenic process are discussed.

Indexed as

Oral MedicineBacillotaBacteria, AnaerobicBacterial AdhesionHumansOxidative StressPeriodontitisCommunity dynamicsFilifactor alocisPeriodontitisPolymicrobial infection

Identifiers

PMID25841800
PMCPMC4485945
OpenAlexW2053701359

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.