Evidence map›Paper›PMID 25841748›Full record

ArticleInfection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases2015

Genomic characterization of a turkey reovirus field strain by Next-Generation Sequencing.

Yi Tang, Huaguang Lu, Aswathy Sebastian, Yin-Ting Yeh, Craig A Praul, Istvan U Albert, Si-Yang Zheng

Abstract read
In one paragraph

Article in Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
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  7. Article
  8. Article
  9. Detection and Identification of Avian Reovirus in Young Geese (Animals : an open access journal from MDPI · 2022
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yi TangWiley Lab/Avian Virology, Department of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA 16802, United States.
Huaguang LuWiley Lab/Avian Virology, Department of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA 16802, United States. Electronic address: hxl15@psu.edu.
Aswathy SebastianDepartment of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, PA 16802, United States.
Yin-Ting YehDepartment of Biomedical Engineering, The Pennsylvania State University, University Park, PA 16802, United States.
Craig A PraulGenomics Core Facility, The Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, PA 16802, United States.
Istvan U AlbertDepartment of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, PA 16802, United States.
Si-Yang ZhengDepartment of Biomedical Engineering, The Pennsylvania State University, University Park, PA 16802, United States.

Funding

Penn State Clinical and Translational Science InstituteUL1TR000127 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI SINOWAY, LAWRENCE I · 2012 to 2015
$17.1M
NCATS NIH HHS UL1 TR000127
6 · The paper itself

Abstract

The genome of a turkey arthritis reovirus (TARV) field strain (Reo/PA/Turkey/22342/13), isolated from a turkey flock in Pennsylvania (PA) in 2013, has been sequenced using Next-Generation Sequencing (NGS) on the Illumina MiSeq platform. The genome of the PA TARV field strain was 23,496bp in length with 10 dsRNA segments encoding 12 viral proteins. The lengths of the genomic segments ranged from 1192bp (S4) to 3959bp (L1). The 5' and 3' conserved terminal sequences of the PA TARV field strain were similar to the two Minnesota (MN) TARVs (MN9 and MN10) published recently and avian orthoreovirus (ARV) reference strains. Phylogenetic analysis of the nucleotide sequences of all 10 genome segments revealed that there was a low to significant nucleotide sequence divergence between the PA TARV field strain and reference TARV and ARV strains. Analysis of the PA TARV sequence indicates that this PA TARV field strain is a unique strain and is different from the TARV MN9 or MN10 in M2 segment genes and ARV S1133 vaccine strain.

Indexed as

Genome, ViralAnimalsConserved SequenceHigh-Throughput Nucleotide SequencingOpen Reading FramesOrthoreovirus, AvianPennsylvaniaPhylogenyPolymorphism, Single NucleotidePoultry DiseasesSequence Analysis, RNATurkeysViral ProteinsViral ProteinsGenome segmentsGenotypingNext-Generation SequencingTurkey arthritis reovirus

Identifiers

PMID25841748
PMCPMC4649943

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.