Evidence map›Paper›PMID 25840600›Full record

Trial reportHaematologica2015

Impact of maintenance therapy on subsequent treatment in patients with newly diagnosed multiple myeloma: use of "progression-free survival 2" as a clinical trial end-point.

Meletios A Dimopoulos, Maria T Petrucci, Robin Foà, John Catalano, Martin Kropff, Evangelos Terpos, Jingshan Zhang, Lara Grote, Christian Jacques, Antonio Palumbo and 1 more

Abstract readClinical Trial, Phase IIILetterMulticenter Study
In one paragraph

Trial report in Haematologica, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
  4. Review
  5. Moving Toward Continuous Therapy in Multiple Myeloma.Clinical hematology international · 2019
    Review
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Meletios A DimopoulosUniversity of Athens School of Medicine, Greece mdimop@med.uoa.gr.
Maria T PetrucciSapienza University of Rome, Italy.
Robin FoàSapienza University of Rome, Italy.
John CatalanoFrankston Hospital, Monash University, Victoria, Australia.
Martin KropffUniversity of Münster, Germany.
Evangelos TerposUniversity of Athens School of Medicine, Greece.
Jingshan ZhangCelgene Corporation, Summit, NJ, USA.
Lara GroteCelgene Corporation, Summit, NJ, USA.
Christian JacquesCelgene Corporation, Summit, NJ, USA.
Antonio PalumboUniversity of Turin, Italy.
MM-015 Investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antineoplastic Combined Chemotherapy ProtocolsDisease-Free SurvivalHumansMaintenance ChemotherapyMultiple MyelomaTreatment OutcomelenalidomidemaintenanceMM-015newly diagnosed multiple myeloma (NDMM)PFS2

Identifiers

PMID25840600
PMCPMC5004436

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.