ArticleVirology2015
Small circular single stranded DNA viral genomes in unexplained cases of human encephalitis, diarrhea, and in untreated sewage.
Article in Virology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
64 citing papers in PubMed.
- Widespread genomic islands are hotspots of genome variations and mosaicism in giant viruses.Nature communications · 2026Article
- Blood and gut virome remodeling in gastric cancer: Anellovirus expansion and novel virus discovery.Virologica Sinica · 2026Article
- Transcriptome Analysis Reveals Gemykibivirus Infection Induces Mitochondrial DNA Release in HEK293T Cells.Viruses · 2025Article
- Identification and characterization of novel CRESS-DNA viruses in the human respiratory tract.Virology journal · 2025Article
- Viral Metagenomics of the Bharal (Polish journal of microbiology · 2025Article
- Metagenomic Identification of a Novel Zoonotic Gemykibivirus in a Diarrheic Pig in China.Transboundary and emerging diseases · 2025Article
- Unveiling the Virome of Wild Birds: Exploring CRESS-DNA Viral Dark Matter.Genome biology and evolution · 2024Article
- 2024 taxonomy update for the family Circoviridae.Archives of virology · 2024Review
- Article
- The Blood Virome: A new frontier in biomedical science.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2024Review
- Gemykibivirus detection in acute encephalitis patients from Nepal.medRxiv : the preprint server for health sciences · 2024Article
- Novel cycloviruses identified by mining human blood metagenomic data show close relationship to those from animals.Frontiers in microbiology · 2024Article
- Unbiased Virus Detection in a Danish Zoo Using a Portable Metagenomic Sequencing System.Viruses · 2023Article
- Comparison of viral communities in the blood, feces and various tissues of wild brown rats (Heliyon · 2023Article
- Article
- A case report of the metagenomics next-generation sequencing for early detection of central nervous system mucormycosis with successful rescue in patient with recurrent chronic lymphocytic leukemia.Annals of translational medicine · 2022Article
- Identification and genomic characterization of a novel porcine CRESS DNA virus from a pig suffering from diarrhea in China.Archives of virology · 2022Article
- Establishment of a Real-Time Quantitative PCR Assay for Porcine Circovirus-Like Virus and the First Evidence of Its Spread to Hainan and Jiangxi Provinces of China.Frontiers in veterinary science · 2022Article
- Article
- Family Genomoviridae: 2021 taxonomy update.Archives of virology · 2021Article
4 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
Viruses with small circular ssDNA genomes encoding a replication initiator protein can infect a wide range of eukaryotic organisms ranging from mammals to fungi. The genomes of two such viruses, a cyclovirus (CyCV-SL) and gemycircularvirus (GemyCV-SL) were detected by deep sequencing of the cerebrospinal fluids of Sri Lankan patients with unexplained encephalitis. One and three out of 201 CSF samples (1.5%) from unexplained encephalitis patients tested by PCR were CyCV-SL and GemyCV-SL DNA positive respectively. Nucleotide similarity searches of pre-existing metagenomics datasets revealed closely related genomes in feces from unexplained cases of diarrhea from Nicaragua and Brazil and in untreated sewage from Nepal. Whether the tropism of the cyclovirus and gemycircularvirus reported here include humans or other cellular sources in or on the human body remains to be determined.
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Registered trials
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