Evidence map›Paper›PMID 25839053›Full record

ArticleTheScientificWorldJournal2015

Evaluation of Cinnamomum osmophloeum Kanehira extracts on tyrosinase suppressor, wound repair promoter, and antioxidant.

Man-Gang Lee, Su-Yu Kuo, Shih-Yu Yen, Hsia-Fen Hsu, Chung-Hang Leung, Dik-Lung Ma, Zhi-Hong Wen, Hui-Min David Wang

Abstract read
In one paragraph

Article in TheScientificWorldJournal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Frontiers in pharmacology · 2021
    Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Man-Gang LeeDepartment of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan ; Division of Urology, Department of Surgery, Zuoying Branch of Kaohsiung Armed Forces General Hospital, Kaohsiung 813, Taiwan.
Su-Yu KuoDepartment of Fragrance and Cosmetic Science, Graduate Institute of Natural Products, Center for Stem Cell Research, Kaohsiung Medical University, No. 100, Shih-Chuan 1st Road, San-Ming District, Kaohsiung 80708, Taiwan.
Shih-Yu YenDepartment of Bioscience Technology, Chang Jung Christian University, Tainan 711, Taiwan.
Hsia-Fen HsuMetal Industries Research & Development Centre, Kaohsiung 812, Taiwan.
Chung-Hang LeungState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau.
Dik-Lung MaDepartment of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong.
Zhi-Hong WenDepartment of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan ; Marine Biomedical Laboratory & Center for Translational Biopharmaceuticals, Department of Marine Biotechnology and Resources, National Sun Yat-sen University, 70 Lien-Hai Road, Kaohsiung 804, Taiwan.
Hui-Min David WangDepartment of Fragrance and Cosmetic Science, Graduate Institute of Natural Products, Center for Stem Cell Research, Kaohsiung Medical University, No. 100, Shih-Chuan 1st Road, San-Ming District, Kaohsiung 80708, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cinnamomum osmophloeum Kanehira belongs to the Lauraceae family of Taiwan's endemic plants. In this study, C. osmophloeum Kanehira extract has shown inhibition of tyrosinase activity on B16-F10 cellular system first. Whether extracts inhibited mushroom tyrosinase activity was tested, and a considerable inhibition of mushroom tyrosinase activity by in vitro assays was presented. Animal experiments of C. osmophloeum Kanehira were carried out by observing animal wound repair, and the extracts had greater wound healing power than the vehicle control group (petroleum jelly with 8% DMSO, w/v). In addition, the antioxidant capacity of C. osmophloeum Kanehira extracts in vitro was evaluated. We measured C. osmophloeum Kanehira extract's free radical scavenging capability, metal chelating, and reduction power, such as biochemical activity analysis. The results showed that a high concentration of C. osmophloeum Kanehira extract had a significant scavenging capability of free radical, a minor effect of chelating ability, and moderate reducing power. Further exploration of the possible physiological mechanisms and the ingredient components of skincare product for skin-whitening, wound repair, or antioxidative agents are to be done.

Indexed as

CinnamomumAnimalsAntioxidantsDrug Evaluation, PreclinicalEnzyme InhibitorsMaleMelanoma, ExperimentalMonophenol MonooxygenasePlant ExtractsPlant LeavesRatsRats, WistarWound HealingAntioxidantsEnzyme InhibitorsMonophenol MonooxygenasePlant Extracts

Identifiers

PMID25839053
PMCPMC4370200

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.