Evidence map›Paper›PMID 25838788›Full record

ArticleInternational journal of mass spectrometry2015

An IMS-IMS threshold method for semi-quantitative determination of activation barriers: Interconversion of proline

Nicholas A Pierson, David E Clemmer

Open access · greenAbstract read
In one paragraph

Article in International journal of mass spectrometry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Action and Ion Mobility Spectroscopy of a Shortened Retinal Derivative.Journal of the American Society for Mass Spectrometry · 2018
    Article
  7. Replacing HChemical science · 2018
    Article
  8. Review
  9. Separation of cis and trans Isomers of Polyproline by FAIMS Mass Spectrometry.Journal of the American Society for Mass Spectrometry · 2016
    Article
  10. Article
  11. Article
  12. Article
  13. "Wet" Versus "Dry" Folding of Polyproline.Journal of the American Society for Mass Spectrometry · 2016
    Article
  14. Infrared Spectroscopy of Mobility-Selected H+-Gly-Pro-Gly-Gly (GPGG).Journal of the American Society for Mass Spectrometry · 2015
    Article
  15. Review
  16. Populations of metal-glycan structures influence MS fragmentation patterns.Journal of the American Society for Mass Spectrometry · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Nicholas A PiersonDepartment of Chemistry, Indiana University, Bloomington, Indiana 47405 United States.
David E ClemmerDepartment of Chemistry, Indiana University, Bloomington, Indiana 47405 United States.
Indiana University Bloomington · US

Funding

New Ion Mobility/Photodissociation Techniques for Analyzing GlycansRC1GM090797 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI CLEMMER, DAVID E. · 2009 to 2010
$955k
NIGMS NIH HHS RC1 GM090797
6 · The paper itself

Abstract

Collisional activation of selected conformations by multidimensional ion mobility spectrometry (IMS-IMS), combined with mass spectrometry (MS), is described as a method to determine semi-quantitative activation energies for interconversion of different structures of the nonapeptide bradykinin (BK, Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg). This analysis is based on a calibration involving collision-induced dissociation measurements of ions with known dissociation energies (i.e., "thermometer" ions) such as leucine enkephalin, BK, and amino acid-metal cation systems. The energetic barriers between six conformations of [BK+3H]

Indexed as

activation energyion mobility spectrometrymulti-dimensionalpeptide conformation

Identifiers

PMID25838788
PMCPMC4378547
OpenAlexW2148180423

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.