ArticleJournal of human reproductive sciences
Should men with idiopathic obstructive azoospermia be screened for genitourinary tuberculosis?
Article in Journal of human reproductive sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The trial behind it
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Who cites it
5 citing papers in PubMed.
- Unilateral Versus Bilateral Vasoepididymal Anastomosis for Idiopathic Obstructive Azoospermia: A Randomised Controlled Trial.European urology open science · 2023Article
- Urogenital tuberculosis - epidemiology, pathogenesis and clinical features.Nature reviews. Urology · 2019Review
- Infertility in the Moroccan population: major risk factors encountered in the reproductive health centre in Rabat.The Pan African medical journal · 2018Article
- Genital tuberculosis: current status of diagnosis and management.Translational andrology and urology · 2017Review
- Relevance of semen polymerase chain reaction positive for tuberculosis in asymptomatic men undergoing infertility evaluation.Journal of human reproductive sciencesArticle
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveInfertility may be the sole manifestation of genitourinary tuberculosis (TB) and men with idiopathic obstructive azoospermia are often screened for TB using semen polymerase chain reaction (PCR) test. We assessed the benefits of such screening.
designTotally, 100 infertile men with idiopathic obstructive azoospermia were screened with a kit-based PCR for semen TB. Confirmatory tests for TB were performed in PCR positive men before administering anti-tubercular therapy (ATT) for 6 months. Semen analysis was repeated to assess benefits of treatment.
resultsSeven subjects (7%) had positive semen PCR for TB. Four of them had other clinical evidence of TB (history and physical signs) and were administered ATT. None had any improvement in semen parameters. No subject had any other laboratory evidence of TB and no other subject (96%) was administered ATT.
conclusionsScreening for TB using semen PCR did not identify any men who would have been missed on clinical evaluation and is thus not indicated in men with idiopathic obstructive azoospermia.
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