Evidence map›Paper›PMID 25838583›Full record

ArticleChemical engineering science2015

Non-Spherical Particles for Targeted Drug Delivery.

Jinrong Chen, Nicholas Clay, Hyunjoon Kong

Abstract read
In one paragraph

Article in Chemical engineering science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Article
  3. Shape Transformation of Polymer Vesicles.Accounts of materials research · 2024
    Article
  4. Review
  5. Article
  6. Morphogenesis of starfish polymersomes.Nature communications · 2023
    Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Targeting inhaled fibers to the pulmonary acinus: Opportunities for augmented delivery from in silico simulations.European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences · 2019
    Article
  15. Article
  16. Article
  17. Transport of ellipsoid fibers in oscillatory shear flows: Implications for aerosol deposition in deep airways.European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences · 2018
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jinrong ChenDepartment of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, 600 South Mathews Avenue, Urbana IL, 61801, USA.
Nicholas ClayDepartment of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, 600 South Mathews Avenue, Urbana IL, 61801, USA.
Hyunjoon KongDepartment of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, 600 South Mathews Avenue, Urbana IL, 61801, USA ; Institute for Genomic Biology, University of Illinois at Urbana-Champaign, 1206 West Gregory Drive, Urbana IL, 61801, USA ; Department of Chemical Engineering, Soongsil University, Seoul, South Korea.

Funding

Nanocells for vascular normalization therapiesR01HL109192 · NHLBI · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI KONG, HYUNJOON · 2011 to 2015
$1.9M
Training the Next Generation of Researchers in Cancer Nanotechnology at the NCI MR25CA154015 · NCI · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI BASHIR, RASHID, NARDULLI, ANN · 2010 to 2014
$1.5M
Nano-sized Cell Guidance System for Ischemic Tissue RepairR21HL097314 · NHLBI · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI KONG, HYUNJOON · 2009 to 2010
$410k
NCI NIH HHS R25 CA154015NHLBI NIH HHS R01 HL109192NHLBI NIH HHS R21 HL097314
6 · The paper itself

Abstract

Nano- and microparticles loaded with various bioimaging contrast agents or therapeutic molecules have been increasingly used for the diagnosis and treatment of diseases and tissue defects. These particles, often a filled or hollow sphere, can extend the lifetime of encapsulated biomedical modalities in circulation and in target tissue. However, there is a great need to improve the drug loading and targeting efficiency of these particles. Recently, several simulation and

Identifiers

PMID25838583
PMCPMC4378540

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.