Evidence map›Paper›PMID 25837714›Full record

ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2016

Neuromyelitis optica spectrum disorders with multiple brainstem manifestations: a case report.

Yao Li, Bin Jiang, Bin Chen, Mingxia Zhao, Chunlai Zhou, Shuhui Wang, Jimei Li, Ruijin Wang

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Can Wernekink commissure syndrome and wall-eyed bilateral internuclear ophthalmoplegia be ascribed to neuromyelitis optica spectrum disorder?Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2017
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Yao LiDepartment of Neurology, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, People's Republic of China.
Bin JiangDepartment of Neurology, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, People's Republic of China.
Bin ChenDepartment of Neurology, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, People's Republic of China.
Mingxia ZhaoDepartment of Neurology, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, People's Republic of China.
Chunlai ZhouDepartment of Neurology, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, People's Republic of China.
Shuhui WangDepartment of Neurology, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, People's Republic of China.
Jimei LiDepartment of Neurology, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, People's Republic of China. jimeili2002@163.com.
Ruijin WangDepartment of Neurology, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, People's Republic of China.
Capital Medical University · CNBeijing Friendship Hospital · CNCapital University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMultiple brainstem manifestations have been rarely reported during the same attack in neuromyelitis optica spectrum disorders (NMOSD). CASE PRESENTATION: We describe a 39-year-old Asian woman presenting multiple brainstem manifestations including intractable nausea and vomiting, vertigo, diplopia, facial palsy, hypogeusia, ophthalmoplegia, hemiplegia, dysphagia and tonic spasm during the same attack. Hypogeusia was transient and recovered without any immunotherapy. The brain MRIs showed progressive multiple lesions in the brainstem. NMO-IgG (aquaporin4-antibody, AQP4-Ab) were positive in both serum and cerebral spinal fluid. The symptoms and signs were controlled after immunosuppressive therapy. No relapse happened during the 15-month follow-up.

conclusionThis report emphasizes multiple brainstem manifestations during the same attack in NMOSD and the most characteristic symptom was reversible hypogeusia.

Indexed as

AdultBrain StemFemaleHumansNeuromyelitis OpticaMultiple brainstem manifestationsNeuromyelitis optica spectrum disordersTransient hypogeusia

Identifiers

PMID25837714
OpenAlexW2031400025

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.