Evidence map›Paper›PMID 25837170›Full record

ArticleYonsei medical journal2015

The effect of specialized continuous renal replacement therapy team in acute kidney injury patients treatment.

Youn Kyung Kee, Eun Jin Kim, Kyoung Sook Park, Seung Gyu Han, In Mee Han, Chang Yun Yoon, Eunyoung Lee, Young Su Joo, Dae Young Kim, Mi Jung Lee and 7 more

Abstract readComparative Study
In one paragraph

Article in Yonsei medical journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Youn Kyung KeeDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
Eun Jin KimDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
Kyoung Sook ParkDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
Seung Gyu HanDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
In Mee HanDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
Chang Yun YoonDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
Eunyoung LeeDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
Young Su JooDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
Dae Young KimDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
Mi Jung LeeDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
Jung Tak ParkDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
Seung Hyeok HanDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
Tae-Hyun YooDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
Beom Seok KimDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
Shin-Wook KangDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
Kyu Hun ChoiDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
Hyung Jung OhDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea. ohjmd@yuhs.ac.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeContinuous renal replacement therapy (CRRT) has been established for critically ill acute kidney injury (AKI) patients. In addition, some centers consist of a specialized CRRT team (SCT) with physicians and nurses. To our best knowledge, however, ona a few studies have yet been carried out on the superiority of SCT management. MATERIALS AND

methodsA total of 551 patients, who received CRRT between January 2008 and March 2009, were divided into two groups based on the controller of CRRT. The impact of the CRRT management on 28-day mortality was compared between two groups by Kaplan-Meier curve and Cox analysis.

resultsDuring the study period, the number of filters used, down-time per day, and intensive care unit length of day were significantly higher in non-SCT group than in SCT group (6.2 hrs vs. 5.0 hrs, p=0.042; 5.0 hrs vs. 3.8 hrs, p<0.001; 27.5 days vs. 21.1 days, p=0.027, respectively), while net ultrafiltration rate was significantly lower in non-SCT group than SCT group (28.0 mL/kg/hr vs. 29.5 mL/kg/hr, p=0.043, respectively). In addition, 28-day mortality rate was significantly lower in SCT group than with non-SCT group (p=0.031). Moreover, Cox regression analysis showed that 28-day mortality rate was significantly lower in SCT control group, even after adjusting for age, gender, severity scores, biomarkers, risk, injury, failure, loss, and end-stage renal disease, and contributing factors (hazard ratio 0.91, p=0.046).

conclusionA well-trained CRRT team could be beneficial for mortality improvement of AKI patients requiring CRRT.

Indexed as

Acute Kidney InjuryAdultAgedAged, 80 and overBiomarkersCritical IllnessFemaleHumansIntensive Care UnitsKaplan-Meier EstimateKidney Failure, ChronicMaleMiddle AgedPatient Care TeamProportional Hazards ModelsRenal Replacement TherapyBiomarkers28-day mortalityacute kidney injurycontinuous renal replacement therapySCT management

Identifiers

PMID25837170
PMCPMC4397434

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.