Evidence map›Paper›PMID 25837035›Full record

ArticleThe European respiratory journal2015

Effects of quitting cannabis on respiratory symptoms.

Robert J Hancox, Hayden H Shin, Andrew R Gray, Richie Poulton, Malcolm R Sears

Open access · bronzeAbstract read
In one paragraph

Article in The European respiratory journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 73 citations in OpenAlex.

  1. Pooled it
  2. Effects of Marijuana Use on Smokers Switching to E-Cigarettes in a Randomized Clinical Trial.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2022
    Trial
  3. Review
  4. Article
  5. Article
  6. Cannabidiol Toxicity Driven by Hydroxyquinone Formation.Chemical research in toxicology · 2025
    Article
  7. Article
  8. Review
  9. Article
  10. Differential Effects of Cannabis and Tobacco on Lung Function in Mid-Adult Life.American journal of respiratory and critical care medicine · 2022
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. [Asthma and cannabis, cocaine or heroin use].Revue des maladies respiratoires · 2020
    Review
  17. Assessing the public health impacts of legalizing recreational cannabis use: the US experience.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2020
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Robert J HancoxDept of Preventive and Social Medicine, Dunedin School of Medicine, Dunedin, New Zealand bob.hancox@otago.ac.nz.
Hayden H ShinDept of Preventive and Social Medicine, Dunedin School of Medicine, Dunedin, New Zealand.
Andrew R GrayDept of Preventive and Social Medicine, Dunedin School of Medicine, Dunedin, New Zealand.
Richie PoultonDept of Psychology, University of Otago, Dunedin, New Zealand.
Malcolm R SearsFirestone Institute for Respiratory Health, Michael de Groote School of Medicine, McMaster University and St Joseph's Healthcare, Hamilton, ON, Canada.
Dunedin Public Hospital · NZSt. Joseph’s Healthcare Hamilton · CAUniversity of Otago · NZ

Funding

TRANSLATION AND DISSEMINATION COREP30DA023026 · NIDA · DUKE UNIVERSITY · PI HOYLE, RICK · 2008 to 2023
$19.6M
Is mental disorder a preventable cause of age-related disease? The Dunedin Study.R01AG032282 · NIA · DUKE UNIVERSITY · PI CASPI, AVSHALOM, MOFFITT, TERRIE E · 2009 to 2025
$9.5M
Uncovering and confirming gene-environment interactions in psychopathologyR01MH077874 · NIMH · DUKE UNIVERSITY · PI CASPI, AVSHALOM · 2007 to 2010
$1.6M
Medical Research Council G0100527Medical Research Council MR/K00381X/1NIA NIH HHS AG032282NIA NIH HHS R01 AG032282NIDA NIH HHS P30 DA023026NIMH NIH HHS MH077874NIMH NIH HHS R01 MH077874
6 · The paper itself

Abstract

Smoking cannabis is associated with symptoms of bronchitis. Little is known about the persistence of symptoms after stopping cannabis use. We assessed associations between changes in cannabis use and respiratory symptoms in a population-based cohort of 1037 young adults. Participants were asked about cannabis and tobacco use at ages 18, 21, 26, 32 and 38 years. Symptoms of morning cough, sputum production, wheeze, dyspnoea on exertion and asthma diagnoses were ascertained at the same ages. Frequent cannabis use was defined as ≥52 occasions over the previous year. Associations between frequent cannabis use and respiratory symptoms were analysed using generalised estimating equations with adjustments for tobacco smoking, asthma, sex and age. Frequent cannabis use was associated with morning cough (OR 1.97, p<0.001), sputum production (OR 2.31, p<0.001) and wheeze (OR 1.55, p<0.001). Reducing or quitting cannabis use was associated with reductions in the prevalence of cough, sputum and wheeze to levels similar to nonusers.Frequent cannabis use is associated with symptoms of bronchitis in young adults. Reducing cannabis use often leads to a resolution of these symptoms.

Indexed as

AdolescentAdultBronchitisCannabisCoughFemaleFollow-Up StudiesHumansMaleMarijuana SmokingNew ZealandPrevalenceRespirationRespiration DisordersRespiratory SoundsSmoking

Identifiers

PMID25837035
PMCPMC4780250
OpenAlexW2098218789

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.