TrialJournal of the American College of Cardiology2015

Relationship of oxidized phospholipids on apolipoprotein B-100 to cardiovascular outcomes in patients treated with intensive versus moderate atorvastatin therapy: the TNT trial.

Young Sup Byun et al.PubMed ↗Full text ↗Publisher ↗

Published long after NCT00327691 ended. The report of the trial’s main result is not on the map, and the numbers here are shown and do not vote.

What the trial testedas reported · 1,503 people · 2015

Not counted

Increased cardiovascular events

2.1×1.2× to 3.6×

Bigger than 9 in 10 for cardiovascular events

As reported

HR 2.08, 95% CI 1.20–3.61

Range includes no effect

No clear effect on cardiovascular events

1.4×0.8× to 2.5×

Bigger than 7 in 10 for cardiovascular events

As reported

HR 1.40, 95% CI 0.80–2.46

Two numbers in the abstract

the abstract, start to end

… MACE compared to the first tertile (HR: 2.08; 95% CI: 1.20 to 3.61; p = 0.01) but this was not significant in the atorvastatin 80-mg group (HR: 1.40; 95% CI: 0.80 to 2.46; p = …

← favours treatmentfavours comparator →

could be chance

Cardiovascular events

HR 2.081.20–3.61

Cardiovascular events

HR 1.400.80–2.46

StatinsCardiovascular events

1 / 3

33 papers cite it

2015

2016

2017

2018

2019

2020

2021

2022

2023

2024

2025

2026

this paperpooled ittrialcites it

The trial

NCT00327691phase 48,600 enrolled1998a later paper about it