Evidence map›Paper›PMID 25835199›Full record

ArticleJournal of neuroscience methods2015

Take the monkey and run.

Kimberley A Phillips, M Karen Hambright, Kelly Hewes, Brian M Schilder, Corinna N Ross, Suzette D Tardif

Abstract read
In one paragraph

Article in Journal of neuroscience methods, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Kimberley A PhillipsDepartment of Psychology, Trinity University, San Antonio, TX 78212, United States; Southwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, TX, United States. Electronic address: kimberley.phillips@trinity.edu.
M Karen HambrightDepartment of Social Sciences, College of Coastal Georgia, Brunswick, GA 31520, United States.
Kelly HewesDepartment of Psychology, Trinity University, San Antonio, TX 78212, United States.
Brian M SchilderDepartment of Anthropology, Center for the Advanced Study of Human Paleobiology, The George Washington University, Washington, DC, United States.
Corinna N RossSouthwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, TX, United States; Department of Biology, Texas A&M University San Antonio, San Antonio, TX, United States.
Suzette D TardifSouthwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, TX, United States; Department of Cellular & Structural Biology, Barshop Institute for Longevity & Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, TX 78245, United States.
Texas Biomedical Research Institute · USCollege of Coastal Georgia · USGeorge Washington University · USThe University of Texas Health Science Center at San Antonio · USTrinity University · US

Funding

The Southwest National Primate Research Center Supplement- Infrastructure improvements of ABSL2 holding areasP51OD011133 · OD · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI Larry S. Schlesinger · 2012 to 2026
$129.7M
NIH HHS P51 OD011133
6 · The paper itself

Abstract

backgroundThe common marmoset (Callithrix jacchus) is a small, New World primate that is used extensively in biomedical and behavioral research. This short-lived primate, with its small body size, ease of handling, and docile temperament, has emerged as a valuable model for aging and neurodegenerative research. A growing body of research has indicated exercise, aerobic exercise especially, imparts beneficial effects to normal aging. Understanding the mechanisms underlying these positive effects of exercise, and the degree to which exercise has neurotherapeutic effects, is an important research focus. Thus, developing techniques to engage marmosets in aerobic exercise would have great advantages. NEW

methodHere we describe the marmoset exercise ball (MEB) paradigm: a safe (for both experimenter and subjects), novel and effective means to engage marmosets in aerobic exercise. We trained young adult male marmosets to run on treadmills for 30 min a day, 3 days a week.

resultsOur training procedures allowed us to engage male marmosets in this aerobic exercise within 4 weeks, and subjects maintained this frequency of exercise for 3 months. COMPARISON WITH EXISTING

methodsTo our knowledge, this is the first described method to engage marmosets in aerobic exercise. A major advantage of this exercise paradigm is that while it was technically forced exercise, it did not appear to induce stress in the marmosets.

conclusionsThese techniques should be useful to researchers wishing to address physiological responses of exercise in a marmoset model.

Indexed as

CallithrixAnimalsBody WeightDefecationMalePhysical Conditioning, AnimalVideo RecordingAging researchExerciseMarmoset (Callithrix jacchus)Primate models

Identifiers

PMID25835199
PMCPMC4464801
OpenAlexW2008750659

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.