ReviewBioMed research international2015
Endocrine and bone complications in β-thalassemia intermedia: current understanding and treatment.
Review in BioMed research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06377865 (Thyroid Function , HbA1c in Relation to Ferritin Level in Adullt Patient e B Thalassemia), which is not on this map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Thyroid Function , HbA1c in Relation to Ferritin Level in Adullt Patient e B Thalassemia
Who cites it
15 citing papers in PubMed, 46 citations in OpenAlex.
- An In-Depth Analysis of Variable Dynamics Influencing Bone Mineral Density in Transfusion-Dependent Thalassemia Patients.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2025Article
- Evaluation of Children and Adolescents with Thalassemia Major in Terms of Osteoporosis: A Single-Centre Experience.Journal of clinical medicine · 2025Article
- A retrospective study of glucose homeostasis, insulin secretion, sensitivity/resistance in non- transfusion-dependent β-thalassemia patients (NTD- β Thal): reduced β-cell secretion rather than insulin resistance seems to be the dominant defect for glucose dysregulation (GD).Acta bio-medica : Atenei Parmensis · 2023Article
- Non-Transfusion-Dependent Thalassemia: A Panoramic Review.Medicina (Kaunas, Lithuania) · 2022Review
- Good Clinical Practice of the Italian Society of Thalassemia and Haemoglobinopathies (SITE) for the Management of Endocrine Complications in Patients with Haemoglobinopathies.Journal of clinical medicine · 2022Article
- Luspatercept: A Gigantic Step in the Treatment of Transfusion-Dependent β-Thalassemia Patients-a Quick Review.Advances in therapy · 2021Review
- Beta-Thalassemia Intermedia: A Single Thalassemia Center Experience from Northeastern Iraq.BioMed research international · 2020Article
- Marital status and paternity in patients with Transfusion- Dependent Thalassemia (TDT) and Non Transfusion-Dependent Thalassemia (NTDT): an ICET - A survey in different countries.Acta bio-medica : Atenei Parmensis · 2019Article
- Final Height and Endocrine Complications in Patients with β-Thalassemia Intermedia: Our Experience in Non-Transfused Versus Infrequently Transfused Patients and Correlations with Liver Iron Content.Mediterranean journal of hematology and infectious diseases · 2019Article
- Prevalence of abnormal glucose homeostasis in Chinese patients with non-transfusion-dependent thalassemia.Diabetes, metabolic syndrome and obesity : targets and therapy · 2019Article
- β-Thalassemia intermedia: a comprehensive overview and novel approaches.International journal of hematology · 2018Review
- Non-Transfusion-Dependent Thalassemia: An Update on Complications and Management.International journal of molecular sciences · 2018Review
- Iron Overload and Chelation Therapy in Non-Transfusion Dependent Thalassemia.International journal of molecular sciences · 2017Review
- Review
- Endocrine disorders in Beta-Thalassemia major patients at a Tertiary Care Hospital.Pakistan journal of medical sciencesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Thalassemia intermedia (TI), also known as nontransfusion dependent thalassemia (NTDT), is a type of thalassemia where affected patients do not require lifelong regular transfusions for survival but may require occasional or even frequent transfusions in certain clinical settings and for defined periods of time. NTDT encompasses three distinct clinical forms: β-thalassemia intermedia (β-TI), Hb E/β-thalassemia, and α-thalassemia intermedia (Hb H disease). Over the past decade, our understanding of the molecular features, pathophysiology, and complications of NTDT particularly β-TI has increased tremendously but data on optimal treatment of disease and its various complications are still lacking. In this paper, we shall review a group of commonly encountered complications in β-TI, mainly endocrine and bone complications.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.