Evidence map›Paper›PMID 25834444›Full record

ArticleNeuropsychiatric disease and treatment2015

Do physical exercise and reading reduce the risk of Parkinson's disease? a cross-sectional study on factors associated with Parkinson's disease in elderly Chinese veterans.

Y M Zou, J P Tan, N Li, J S Yang, B C Yu, J M Yu, Y M Zhao, L N Wang

Open access · goldAbstract read
In one paragraph

Article in Neuropsychiatric disease and treatment, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. The Contribution of Physical Exercise to Brain Resilience.Frontiers in behavioral neuroscience · 2020
    Review
  2. Review
  3. Epidemiology of Parkinson's Disease-East Versus West.Movement disorders clinical practice
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Y M ZouDepartment of Neurology, Huanhu Hospital, Tianjin, People's Republic of China.
J P TanDepartment of Geriatric Neurology, Chinese PLA General Hospital, Peking University Third Hospital, Beijing, People's Republic of China.
N LiResearch Center of Clinical Epidemiology, Peking University Third Hospital, Beijing, People's Republic of China.
J S YangDepartment of Neurology, General Hospital of Lanzhou Military Command, Lanzhou, People's Republic of China.
B C YuDepartment of Gerontology, Bethune International Peace Hospital, Shijiazhuang, People's Republic of China.
J M YuDepartment of Neurology, Chinese PLA 107 Hospital, Yantai, People's Republic of China.
Y M ZhaoResearch Center of Clinical Epidemiology, Peking University Third Hospital, Beijing, People's Republic of China.
L N WangDepartment of Geriatric Neurology, Chinese PLA General Hospital, Peking University Third Hospital, Beijing, People's Republic of China.
Peking University · CNPeking University Third Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe purpose of this study was to investigate risk factors for and factors protecting against Parkinson's disease (PD) in elderly Chinese veterans.

methodsUsing a database containing detailed information on the health status of the nervous system in elderly Chinese veterans, univariate and multivariate analyses of factors that may be associated with PD were performed. Univariate analysis of qualitative data was done using the Pearson Chi-square and Fisher's exact tests, and the Mann-Whitney U nonparametric test was used for univariate analysis of quantitative data. Multivariate logistic regression analysis was used to identify independent risk factors for and factors protecting against PD in elderly Chinese veterans.

resultsA total of 9,676 elderly Chinese veterans were enrolled, including 228 cases with PD and 183 cases with Parkinson's syndrome, with 9,265 non-PD subjects serving as controls. Age (odds ratio [OR] 1.343, 95% confidence interval [CI] 1.028-1.755) and medical history of essential tremor (OR 1.228, 95% CI 1.081-1.396) were identified as independent risk factors for PD, with age being the most important risk factor. Physical exercise (OR 0.478, 95% CI 0.355-0.643) and reading (OR 0.513, 95% CI 0.357-0.735) were identified as independent factors protecting against PD, and physical exercise showed better protection against PD relative to reading. Smoking, alcohol use, anemia, cerebral trauma, education level, and electromagnetic field exposure showed no association with PD.

conclusionPhysical exercise and reading may be independent factors that protect against PD among elderly Chinese veterans, while advancing age and medical history of essential tremor may be independent risk factors for PD. This study was cross-sectional, so further research is needed to confirm its results.

Indexed as

ageChinese veteransessential tremormedical historyParkinson’s diseasephysical exercisereading

Identifiers

PMID25834444
PMCPMC4370918
OpenAlexW1981158423

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.