ArticleWorld journal of gastroenterology2015
Differences in clinical features of Crohn's disease and intestinal tuberculosis.
Article in World journal of gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- Meta-Analytic Bayesian Model For Differentiating Intestinal Tuberculosis from Crohn's Disease.The American journal of gastroenterology · 2017Pooled it
- The Overlap Between Crohn's Disease and Intestinal Tuberculosis: A Never-Ending Story.Medicina (Kaunas, Lithuania) · 2026Review
- Rectal tuberculosis in a 48-years-old immuno-competent man: A rare case report.International journal of surgery case reports · 2025Article
- Complicated enteroenteric intestinal fistula due to Crohn's disease: a rare case report.Journal of surgical case reports · 2025Article
- Differential diagnosis of Crohn's disease and intestinal tuberculosis based on ATR-FTIR spectroscopy combined with machine learning.World journal of gastroenterology · 2024Article
- Differentiating gastrointestinal tuberculosis and Crohn's disease- a comprehensive review.BMC gastroenterology · 2023Review
- Intestinal tuberculosis can masquerade as Crohn's disease: A teachable moment.SAGE open medical case reports · 2023Article
- Development and validation of a new algorithm model for differential diagnosis between Crohn's disease and intestinal tuberculosis: a combination of laboratory, imaging and endoscopic characteristics.BMC gastroenterology · 2021Article
- A Novel Clinical Radiomics Nomogram to Identify Crohn's Disease from Intestinal Tuberculosis.Journal of inflammation research · 2021Article
- Intestinal tuberculosis or Crohn's disease: a review of the diagnostic models designed to differentiate between these two gastrointestinal diseases.Intestinal research · 2021Review
- Article
- Effect of Age on the Initiation of Biologic Agent Therapy in Patients With Inflammatory Bowel Disease: Korean Common Data Model Cohort Study.JMIR medical informatics · 2020Article
- Levels of TB-IGRA may help to differentiate between intestinal tuberculosis and Crohn's disease in patients with positive results.Therapeutic advances in gastroenterology · 2020Article
- Article
- Serum proteome profiles to differentiate Crohn disease from intestinal tuberculosis and primary intestinal lymphoma: A pilot study.Medicine · 2019Article
- Comparison of outcomes of continuation/discontinuation of 5-aminosalicylic acid after initiation of anti-tumor necrosis factor-alpha therapy in patients with inflammatory bowel disease.International journal of colorectal disease · 2019Article
- Ten Cases of Intestinal Tuberculosis Which Were Initially Misdiagnosed as Inflammatory Bowel Disease.Internal medicine (Tokyo, Japan) · 2019Article
- Differentiating Crohn's disease from intestinal tuberculosis.World journal of gastroenterology · 2019Review
- Diagnostic delay in inflammatory bowel disease increases the risk of intestinal surgery.World journal of gastroenterology · 2017Observational
- Temporal trends in the misdiagnosis rates between Crohn's disease and intestinal tuberculosis.World journal of gastroenterology · 2017Observational
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo investigate the clinical features of Crohn's disease (CD) and intestinal tuberculosis (ITB) with a scoring system that we have developed.
methodsA total of 25 CD and 40 ITB patients were prospectively enrolled from August 2011 to July 2012. Their characteristics and clinical features were recorded. Laboratory, endoscopic, histologic and radiographic features were determined. The features with a high specificity were selected to establish a scoring system. The features supporting CD scored +1, and those supporting ITB scored -1; each patient received a final total score. A receiver operating characteristic (ROC) curve was used to determine the best cut-off value for distinguishing CD from ITB.
resultsBased on a high specificity of differentiating between CD and ITB, 12 features, including longitudinal ulcers, nodular hyperplasia, cobblestone-like mucosa, intestinal diseases, intestinal fistula, the target sign, the comb sign, night sweats, the purified protein derivative test, the interferon-γ release assay (T-SPOT.TB), ring ulcers and ulcer scars, were selected for the scoring system. The results showed that the average total score of the CD group was 3.12 ± 1.740, the average total score of the ITB group was -2.58 ± 0.984, the best cutoff value for the ROC curve was -0.5, and the diagnostic area under the curve was 0.997, which was statistically significant (P < 0.001). The patients whose total scores were higher than -0.5 were diagnosed with CD; otherwise, patients were diagnosed with ITB. Overall, the diagnostic accuracy rate and misdiagnosis rate of this scoring system were 97% and 3%, respectively.
conclusionSome clinical features are valuable for CD and ITB diagnosis. The described scoring system is key to differentiating between CD and ITB.
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